What is the pregnancy category for loratadine?
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What is the pregnancy category for loratadine?
If a second generation agent has to be used then loratadine or cetirizine should be preferred as they have been widely studied for possible teratogenic effects and have been found to be nonteratogenic till date. Both these agents are pregnancy category B agents.
Which antihistamine is safe in pregnancy?
ANSWER First-generation antihistamines are considered safe to use during pregnancy. There are relatively fewer data on the nonsedating second-generation antihistamines; however, published studies are reassuring.
Does loratadine cross the placenta?
Loratadine / pseudoephedrine Pregnancy Warnings Loratadine: Animal studies at up to 150 times the maximum recommended human dose found no teratogenicity. It is unknown if it crosses the placenta, but it is probable with its low molecular weight (about 383).
Is loratadine safe during first trimester?
There is currently no concern that exposure to loratadine in early pregnancy is linked to birth defects in the baby.
Is loratadine safe in first trimester?
There is currently no concern that exposure to loratadine in early pregnancy is linked to birth defects in the baby. However, relatively small numbers of women taking loratadine have been studied and ongoing research is required to confirm this.
What can I take for allergies while pregnant first trimester?
These over-the-counter allergy meds have no known harmful effects during pregnancy when you take them according to the package directions.
- Allegra (fexofenadine)
- Benadryl (diphenhydramine)
- Claritin (loratadine)
- Zyrtec (cetirizine)
What is Category C drug in pregnancy?
Category C: Studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women, or studies in women and animals are not available. Drugs from this class can be given to pregnant women if the benefit to the mother outweighs the risk to the fetus.
Is cetirizine good for a pregnant woman?
Second-generation antihistamines, such as cetirizine (CTZ) and loratadine, are considered safe in pregnancy and are not associated with an increased risk for major congenital malformations (Li et al.
What helps allergies when pregnant?
Step-by-Step Care:
- Try to avoid your allergy triggers.
- Use saline nose spray to ease your congestion.
- Keep animals out of your bedroom.
- Vacuum often.
- Use the air conditioner to keep humidity low and irritants out of the house.
- Shower and wash your hair after being outdoors if pollen sets off your allergies.
What does class C mean for pregnancy?
Category C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.
What birth defects are caused by antihistamines?
Researchers found the evidence to be generally reassuring: most antihistamines do not appear to be linked to birth defects.
Is it safe to take Claritin when pregnant?
Many allergy medications really aren’t safe to take during pregnancy. But loratadine (found in Claritin®) and cetirizine (found in Zyrtec® and Alleroff®) are two over-the-counter (OTC) antihistamine medications that doctors consider as being safe to use during pregnancy and while breastfeeding, Dr. Zanotti says.
Does Claritin cause miscarriage?
A study of 161 people taking loratadine during the first trimester of pregnancy did not show an increased chance for miscarriage.