Does nifedipine cause leg swelling like amlodipine?

Does nifedipine cause leg swelling like amlodipine?

Amlodipine and nifedipine are common drugs associated with vasodilatory edema. When used as monotherapy, calcium channel blockers (CCBs) are associated with a substantial risk of peripheral edema, including pedal edema, which is the most common reason for its discontinuation.

Which DHP calcium channel blocker causes the least edema?

Ankle oedema appears to occur more frequently in CCBs from the DHP group, although some agents such as lacidipine and lercanidipine may cause it less frequently than nifedipine and amlodipine. Diltiazem, a non-DHP agent, seems to be associated with the lowest incidence of ankle oedema.

Which calcium channel blocker causes the most edema?

Pedal edema is one of the most common adverse effects of calcium antagonists. It has been observed with all available dihydropyridine agents, but it also seems to occur to a lesser extent with verapamil and diltiazem.

Which calcium channel blockers do not cause edema?

Edema will diminish upon conversion from a dihydropyridine CCB to a nondihydropyridine CCB such as verapamil or diltiazem. In addition, the newer, third-generation dihydropyridine CCBs such as lacidipine,[32,33] manidipine, and lercanidipine[32,33,34,35] are regularly reported to cause less peripheral edema.

Should I stop taking amlodipine if my ankles swell?

Swelling from amlodipine is a common, but often troublesome side effect of amlodipine with 5% to 9% of people stopping amlodipine because of it. If you develop swelling with amlodipine, tell your doctor right away because they may be able to change your blood pressure medications slightly to help reduce the swelling.

Does nifedipine cause fluid retention?

This medicine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of the face, arms, hands, lower legs, or feet; tingling of the hands or feet; or unusual weight gain or loss.

Should you stop taking amlodipine If your ankles swell?

Does nifedipine cause swollen ankles?

Does nifedipine cause swollen legs?

Does amlodipine cause fluid retention?

Summary. Norvasc (amlodipine besylate) is a type of drug called a calcium channel blocker used to treat high blood pressure and angina. One of the more common side effects of Norvasc is edema, or the abnormal swelling of tissue due to the build-up of fluid.

Does nifedipine swelling go away?

Due to the relaxation effect nifedipine has on the smooth muscle in peripheral blood vessels, nifedipine is also associated with edema (discussed below). The additional fluid retention can cause weight gain, however, this usually resolves with stopping the medication or making dose adjustments.

Does amlodipine cause water retention?

by Drugs.com Weight gain with amlodipine may also be a symptom of edema, which is when you retain fluid, which may be particularly noticeable around your ankles or lower legs.

How do I get rid of edema in my legs?

We’ve rounded up some of the best ways you can alleviate swelling in your legs and feet.

  1. Stay Hydrated.
  2. Soak Your Legs in a Salt Bath.
  3. Eliminate Suspected Food Allergies.
  4. Invest in Compression Socks.
  5. Get Moving.
  6. Reduce Salt Intake.
  7. Try Lymphatic Drainage.
  8. Elevate Your Feet.

Does nifedipine cause water retention?

Why does nifedipine cause edema?

The reduced compliance of the blood vessels results in leakage and pooling of extracellular and lymphatic fluids. This is most commonly seen in the lower legs and feet. CCBs, including nifedipine, are known to cause peripheral edema.

Is walking good for edema in legs?

Movement. Moving and using the muscles in the part of your body affected by edema, especially your legs, may help pump the excess fluid back toward your heart.

Does nifedipine make your legs swell?

Nifedipine may cause fluid retention (edema) in some patients. Tell your doctor right away if you have bloating or swelling of the face, arms, hands, lower legs, or feet; tingling of the hands or feet; or unusual weight gain or loss.

How do you push fluid out of your legs?

The first thing your doctor may try are diuretics, or water pills. This may not be the best treatment particularly if the swelling is not due to too much volume. “Often, using counter pressure, or wearing compression stockings, to help push fluid out of the legs is the most effective treatment,” says Dr.

  • August 4, 2022