Is Cevimeline an alkaloid?

Is Cevimeline an alkaloid?

Cevimeline (trade name Evoxac) is a synthetic analog of the natural alkaloid muscarine with a particular agonistic effect on M1 and M3 receptors. It is used in the treatment of dry mouth and Sjögren’s syndrome.

What type of drug is Cevimeline?

Cevimeline is used to treat the symptoms of dry mouth in patients with Sjogren’s syndrome (a condition that affects the immune system and causes dryness of certain parts of the body such as the eyes and mouth). Cevimeline is in a class of medications called cholinergic agonists.

Which is better pilocarpine and Cevimeline?

Conclusion: Both drugs showed efficacy in increasing the salivary flow in healthy volunteers, but cevimeline was more effective than pilocarpine.

What is Cevimeline hcl used for?

Descriptions. Cevimeline is used to treat the symptoms of dry mouth often experienced by patients with Sjögren’s syndrome. It works by causing certain glands in the mouth to produce more saliva. This medicine is available only with your doctor’s prescription.

What are the side effects to cevimeline?

Side Effects

  • Bladder pain.
  • bloody or cloudy urine.
  • body aches or pain.
  • difficult, burning, or painful urination.
  • difficulty in breathing.
  • dryness or soreness of the throat.
  • ear congestion.
  • frequent urge to urinate.

Can I stop taking cevimeline?

Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking except on the advice of your doctor or health care professional.

Does cevimeline cause insomnia?

Sweating, nausea, runny nose, flushing, frequent urge to urinate, dizziness, weakness, diarrhea, and blurred vision may occur….What is Prescribing information?

Adverse Event Cevimeline 30 mg (tid) n*=533 Placebo (tid) n=164
Insomnia 2.4% 1.2%
Hot Flushes 2.4% 0.0%
Rigors 1.3% 1.2%
Anxiety 1.3% 1.2%

Can you just stop taking Cevimeline?

What drugs interact with Cevimeline?

Some products that may interact with this drug include: beta blockers (such as metoprolol, atenolol). Other medications can affect the removal of cevimeline from your body, which may affect how cevimeline works. Examples include cimetidine, amiodarone, ritonavir, fluoxetine, among others.

Can Cevimeline cause weight gain?

Check with your doctor right away if you have chest pain or tightness, decreased urine output, dilated neck veins, extreme fatigue, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, troubled breathing, or weight gain.

  • August 21, 2022