What is conjugated equine estrogen used for?
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What is conjugated equine estrogen used for?
Abstract. Oral conjugated equine estrogens (CEE) are the most used estrogen formulation for postmenopausal hormone therapy either alone or in combination with a progestin. CEE is most commonly used for the management of early menopausal symptoms such as hot flashes, vaginitis, insomnia, and mood disturbances.
What is conjugated equine estrogen made from?
Conjugated estrogens are a mixture of several different estrogens (estrogen salts) that are derived from natural sources and blended to approximate the composition of estrogens in the urine of pregnant horses. The main components are sodium estrone sulphate and sodium equilin sulfate.
Is conjugated estrogen the same as estradiol?
Estradiol is a form of estrogen, a female hormone. All estradiol products are estrogen. However, there are other forms of estrogen than just estradiol. For example, conjugated estrogens (Premarin) is another form of estrogen.
What is the difference between conjugated and unconjugated estrogen?
Unconjugated estrogens (eg, equilin) are absorbed more rapidly than conjugated estrogens (eg, equilin sulfate), but they are soon conjugated by the liver (first-pass effect) and circulate together with E1S as a hormonally inert estrogen reservoir.
What is the side effects of conjugated estrogens?
Stomach upset, nausea/vomiting, bloating, breast tenderness, headache, or weight changes may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Tell your doctor promptly if you see the tablet in your stool.
What is the best alternative to Premarin?
Top 5 Premarin alternatives
- Estrace. Estrace is one brand name used for estradiol preparations.
- EstroGel. EstroGel is a topical gel consisting of 0.06% estradiol.
- Prempro. Prempro is an oral tablet preparation of 0.3 mg/1.5 mg conjugated estrogens/medroxyprogesterone.
- Estring.
- Vivelle-Dot.
Is conjugated estrogen harmful?
Conjugated estrogens may increase your risk of developing a condition that can lead to uterine cancer. Report any unusual vaginal bleeding right away. Using this medicine can increase your risk of blood clots, stroke, heart attack, or cancer of the breast, uterus, or ovaries.
