What is BNP test normal range?
Table of Contents
What is BNP test normal range?
For people who don’t have heart failure, normal BNP levels are less than 100 picograms per milliliter (pg/mL). BNP levels over 100 pg/mL may be a sign of heart failure. For NT-proBNP, normal levels are less than 125 pg/mL for people under 75 years old and less than 450 pg/mL for people over age 75.
What does an increased BNP level indicate?
BNP levels go up when the heart cannot pump the way it should. A result greater than 100 pg/mL is abnormal. The higher the number, the more likely heart failure is present and the more severe it is. Sometimes other conditions can cause high BNP levels.
What does proBNP measure?
The NT-proBNP blood test measures brain natriuretic peptides to detect heart failure. If your doctor orders a BNP test, you are probably showing symptoms of heart failure. The test measures a hormone called “brain natriuretic peptide.”
How do you interpret BNP?
Interpreting BNP Measurements for Heart Failure in Different Clinical Settings. BNP = brain natriuretic peptide; LR+ = positive likelihood ratio; LR– = negative likelihood ratio. *—Based on an assumed LR+ of 5.0 for > 150 pg per mL, LR+ of 0.57 for 50 to 150 pg per mL, and LR– of 0.08 for < 50 pg per mL.
What pro BNP level indicates heart failure?
While a cut point of 300 pg/ml is proposed to rule out the diagnosis of heart failure, for patients younger than 50 years old, between 50-75 and above 75 NT-proBNP levels respectively > 450 pg/ml, > 900 pg/ml, and > 1800 pg/ml have high likelihood of heart failure.
Is BNP specific to heart failure?
The sensitivity of BNP in heart failure is approximately 97%. Therefore a normal BNP level (less than 100 pg/ml) virtually excludes heart failure and should prompt a search for noncardiac causes of dyspnea.
What other conditions can cause high BNP levels?
Other conditions that are associated with a high BNP other than congestive heart failure include:
- Acute renal failure and chronic renal failure. Patients on dialysis.
- Dehydration.
- High blood pressure (hypertension)
- Lung diseases. Pulmonary hypertension.
- Cardiac causes.
- Older age.
- Female sex.
- Liver cirrhosis.
What other conditions can cause BNP to be high?
Can dehydration cause elevated BNP?
Furthermore, levels of BNP can remain high even after achieving an adequate hydration status because of a stretched myocardium (i.e., dry BNP), renal failure, liver failure, pulmonary embolus, and acute coronary syndromes [6, 10].
Can you have a high BNP without heart failure?
Conclusion. BNP is a strong predictor of death in patients with and without HF. The risk of death associated with elevated BNP levels is similar between patients with and those without HF. These data suggest that increased BNP values in patients without HF are important in clinical practice.