What is the F7 gene?

What is the F7 gene?

Normal Function The F7 gene provides instructions for making a protein called coagulation factor VII. Coagulation factors are a group of related proteins that are involved in the coagulation system, which is a series of chemical reactions that form blood clots.

What is F7 test?

This is a next generation sequencing (NGS) test appropriate for individuals with clinical signs and symptoms, suspicion of, or family history of Factor VII Deficiency. Sequence variants and/or copy number variants (deletions/duplications) within the F7 gene will be detected with >99% sensitivity.

Is Factor 7 inherited?

Inheritance. Congenital factor VII deficiency is inherited in an autosomal recessive pattern , which means both copies of the F7 gene in each cell have mutations.

What is factor VII in blood clotting?

Factor VII, also called proconvertin, is one such clotting factor produced by the liver. It requires vitamin K for its production. Along with other clotting factors and blood cells, it promotes blood clotting at the site of an injury. It forms normal blood clots and closes the wound to prevent blood loss.

What does F8 gene do?

The F8 gene provides instructions for making a protein called coagulation factor VIII. Coagulation factors are a group of related proteins that are essential for the formation of blood clots. After an injury, clots protect the body by sealing off damaged blood vessels and preventing further blood loss.

Can factor 7 deficiency be cured?

Inherited factor VII deficiency is a lifelong condition. The outlook for acquired factor VII deficiency depends on the cause. If it is caused by liver disease, the outcome depends on how well your liver disease can be treated. Taking vitamin K supplements will treat vitamin K deficiency.

Is vitamin K deficiency hereditary?

Abstract. Combined deficiency of vitamin K-dependent clotting factors is usually an acquired clinical problem, often resulting from liver disease, malabsorption or warfarin overdose. However, an inherited form of the disease is very rare.

What is Factor VII deficiency?

Factor VII (seven) deficiency is a disorder caused by a lack of a protein called factor VII in the blood. It leads to problems with blood clotting (coagulation). Blood clotting normally occurs when there is damage to a blood vessel.

What tests come fever profile?

It includes Alanine aminotransferase (ALT/SGPT), Complete urine examination, Complete blood count (CBC), Erythrocyte sedimentation rate (ESR), Malarial antigen (Vivax and Falciparum), Peripheral smear for malarial parasite (MP), and Typhoid IgM test.

Is factor 7 a hemophilia?

Factor VII (7) deficiency is an inherited bleeding disorder caused when a person’s body does not produce enough of a protein in the blood (factor VII or FVII) that helps blood clot or the factor VII doesn’t work properly. The disorder is rare, affecting one in 500,000 people.

How is Factor VII deficiency treated?

The main treatment for FVII deficiency is recombinant factor VIIa (rFVIIa). Prothrombin complex concentrates (PCCs) can also be used, but the amount of factor VII they contain can vary considerably. Fresh frozen plasma (FFP) is another option. In some patients, the use of FFP has led to blood clots.

What is the F9 gene?

The F9 gene provides instructions for making a protein called coagulation factor IX. Coagulation factors are a group of related proteins that are essential for the formation of blood clots. After an injury, clots protect the body by sealing off damaged blood vessels and preventing further blood loss.

What is the reason for viral fever?

A viral fever is caused by infection with a virus. Viruses are very small infectious agents. They infect and multiply within the cells of your body. A fever is your body’s way of fighting off a virus.

What is the name Blood Test in fever?

A fever profile test may include more than one test. Here is a list of lab tests. Complete Haemogram (CBC+ESR) Dengue Antigen NS1 Dengue IgG & IgM TyphiDot IgM Peripheral Smear for Malaria Urine Routine Examination These fever profile tests and its price may vary from one diagnostic centre to another.

What is the function of the F7 gene?

Learn more The F7 gene provides instructions for making a protein called coagulation factor VII. Coagulation factors are a group of related proteins that are involved in the coagulation system, which is a series of chemical reactions that form blood clots.

What does F7 stand for?

F7 (Coagulation Factor VII) is a Protein Coding gene. Diseases associated with F7 include Factor Vii Deficiency and Myocardial Infarction . Among its related pathways are Metabolism of proteins and Circadian rythm related genes . Gene Ontology (GO) annotations related to this gene include calcium ion binding and serine-type endopeptidase activity .

What is coagulation factor VII (F7)?

F7 (Coagulation Factor VII) is a Protein Coding gene. Diseases associated with F7 include Factor Vii Deficiency and Myocardial Infarction. Among its related pathways are Metabolism of proteins and Complement and coagulation cascades.

What is the mutational spectrum of the f7gene?

(A) The mutational spectrum of F7gene including different types of variants. Point mutations and gene deletions comprise more than 90% of these variants. Interestingly, most of the point mutations in coding sequence of the gene are missense.