How rare is Mazabraud syndrome?

How rare is Mazabraud syndrome?

Only 107 cases have been reported in the global literature (as of 2019) 1,3-5,15. The prevalence is ~ 1 in 1,000,000 3 with a strong female predilection (68-84%) 1,3. The age at diagnosis ranges from 35-60 years with a mean age of approximately 40 years 1,3. Childhood-onset has been reported in four cases 3.

How rare is fibrous dysplasia?

Fibrous dysplasia (FD) is one of those conditions. With an estimated prevalence of 1 in 15000-30000 individuals , it is unsurprising that I had never come across it.

What is fibrous dysplasia?

Fibrous dysplasia is an uncommon bone disorder in which scar-like (fibrous) tissue develops in place of normal bone. This irregular tissue can weaken the affected bone and cause it to deform or fracture.

What causes intramuscular myxoma?

Intramuscular myxoma is an uncommon benign soft tissue tumor that may arise from fibroblasts that produce an excessive amount of mucopolysacchrides. It is typically seen in adults in the large muscles of extremities and exhibits typical radiological features on sonography and magnetic resonance imaging.

Is McCune-Albright syndrome fatal?

Outlook / Prognosis Prognosis is dependent on the severity of the diagnosis in your child. Most people diagnosed with McCune-Albright syndrome have a normal life expectancy.

Is McCune-Albright rare?

McCune-Albright syndrome (MAS) is an extremely rare disorder that classically affects the bones, skin, and endocrine system.

What is the treatment for myxoma?

Treatment is necessary to avoid metastasis and the formation of clots. In addition, untreated growth of the tumor can obstruct blood flow through the heart. Myxomas are curable with surgical removal. A myxoma is a benign tumor in the heart most commonly found in the left atrium.

Is FOP disease painful?

FOP may eventually result in complete immobilization. Affected individuals may experience progressive pain and stiffness in affected areas, complete fusion of the spine, and/or pain in affected areas of the body caused by abnormal bony growths that compress the nerves in these areas (entrapment neuropathies).

What are symptoms associated with McCune-Albright syndrome?

McCune-Albright syndrome may also affect the thyroid. The thyroid gland, located at the base of the neck, may become enlarged. About half of people with the syndrome produce excess thyroid. Symptoms include a fast heart rate, high blood pressure, weight loss, tremors and sweating.

What are the symptoms of McCune-Albright syndrome?

What are the symptoms of McCune-Albright syndrome?

• Asymmetrical bone growth of the face.
• Bone pain and discomfort.
• Loss of mobility.
• Rickets or osteomalacia.
• Scoliosis.
• Short stature.
• Uneven bone growth of the legs (causing a limp).