What is a serous borderline tumor?
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What is a serous borderline tumor?
Ovarian serous borderline tumor (SBT) is a low grade epithelial neoplasm of generally younger women with a favorable prognosis when diagnosed at an early stage. Defined, nonobligate precursor to low grade serous carcinoma (LGSC)
Is a borderline tumor benign?
Borderline ovarian tumors, often referred to as “low malignant potential” tumors, are not invasive but also not completely benign. Their behavior can also vary based on microscopic features, and some are more likely to recur or spread than others.
What does an elevated CA 125 mean?
An elevated level of CA 125 could prompt your provider to put you through unnecessary and possibly harmful tests. To check for cancer recurrence. Rising CA 125 levels may indicate that ovarian cancer has come back after treatment.
WHO classification borderline ovarian tumors?
Borderline ovarian tumors (BOT) are neoplasms of epithelial origin characterized by up-regulated cellular proliferation and the presence of slight nuclear atypia but without destructive stromal invasion [1].
How do you code serous borderline tumor of ovary?
Benign neoplasm of unspecified ovary
- borderline malignancy D39.1-
- proliferating D39.1-
What is low grade serous carcinoma?
Low grade serous cancer is a type of carcinoma (epithelial cell cancer). It is usually hormone receptor positive (estrogen +/- progesterone). Epithelial ovarian cancer is the most common type of ovarian cancer. Approximately 10% of epithelial serous ovarian cancers are low-grade.
What is considered a high level of CA 125?
Generally speaking, the normal range of CA-125 is considered to be 0-35 units/mL, while a level above 35 units/mL is considered to be a high CA-125 level.
Are borderline ovarian tumors hereditary?
Many studies of BOT are ongoing, but few are evaluating the hereditary risk. Our study reveals a potential hereditary risk of cancer among BOT patients and suggests that between 3% and 19% of patients may need genetic counseling and confirmative testing.
What is the difference between high grade and low grade serous carcinoma?
Low-grade tumors are indolent and have better outcome than high-grade tumors. In contrast, high-grade serous carcinomas have high-grade nuclei and numerous mitotic figures. Identification of a precursor lesion in the ovary has been elusive and therefore the origin of ovarian carcinoma has been described as de novo.
