Does desipramine help with pain?

Does desipramine help with pain?

Desipramine relieves pain caused by diabetic neuropathy with efficacy similar to that of amitriptyline, offering an alternative for patients unable to tolerate the latter. Blockade of norepinephrine reuptake is likely to mediate the analgesic effect of these antidepressant drugs in diabetic neuropathy.

Is desipramine good for nerve pain?

Desipramine is a tricyclic antidepressant from the same class of medicines as amitriptyline, which is widely recommended for treating neuropathic pain.

What is desipramine used to treat?

Desipramine is used to treat depression. Desipramine is in a class of medications called tricyclic antidepressants. It works by increasing the amounts of certain natural substances in the brain that are needed for mental balance.

Can tricyclic antidepressants be used for pain?

Tricyclic antidepressants are the most common type of antidepressant used for pain. They include: Amitriptyline. Nortriptyline (Pamelor)

Is is desipramine the same as amitriptyline?

Elavil (amitriptyline) regulates mood and treats nerve pain, but has more side effects than alternatives. Stabilizes your mood. Norpramin (desipramine) is not a first choice for treating depression because of its effects on the heart, but it can be good if other medicines haven’t worked.

Does desipramine give you energy?

Desipramine Uses: This medication may improve your mood, sleep, appetite, and energy level, as well as help you regain interest in your daily activities. This medication belongs to the class of drugs known as tricyclic antidepressants.

Who should not take desipramine?

Its use isn’t recommended in people ages 18 years and younger. This drug may cause suicidal thoughts and behaviors in children, adolescents, and young adults during the first few months of use.

Why do tricyclics help pain?

Tricyclic antidepressants may relieve neuropathic pain by their unique ability to inhibit presynaptic reuptake of the biogenic amines serotonin and noradrenaline, but other mechanisms such as N-methyl-D-aspartate receptor and ion channel blockade probably also play a role in their pain-relieving effect.

Does desipramine make you tired?

The dosage is based on your medical condition and response to treatment. Your doctor may start you at a low dose and gradually increase your dose. This medication may make you sleepy or wakeful.

Can desipramine cause weight gain?

Yes, tricyclic antidepressants like desipramine (Norpramin) can cause weight gain. However, some people have lost weight while on this medication.

Does desipramine make you gain weight?

What is the difference between amitriptyline and desipramine?

What antidepressants help with arthritis pain?

In fact, some guidelines for the treatment of chronic low back pain and osteoarthritis (the most common type of arthritis) include antidepressants. One antidepressant in particular, duloxetine (Cymbalta), is FDA-approved for these conditions.