How much does Nexletol lower cholesterol?
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How much does Nexletol lower cholesterol?
High LDL, or bad cholesterol, is one of the top risks for heart attacks and other problems. Studies showed that Nexletol could lower LDL by about 25% when taken alone and by an additional 18% when combined with a statin.
Does ezetimibe lower total cholesterol?
Ezetimibe works by reducing the amount of cholesterol your body takes in from your food. It is usually prescribed alongside a cholesterol-lowering diet. Ezetimibe can often be prescribed together with a statin to further lower your cholesterol levels.
Are statins good for you?
Statins are effective at lowering cholesterol and protecting against a heart attack and stroke, although they may lead to side effects for some people. Doctors often prescribe statins for people with high cholesterol to lower their total cholesterol and reduce their risk of a heart attack or stroke.
Do statins lower cholesterol?
Statins are a group of medicines that can help lower the level of low-density lipoprotein (LDL) cholesterol in the blood. LDL cholesterol is often referred to as “bad cholesterol”, and statins reduce the production of it inside the liver.
Which is better statins or ezetimibe?
Ezetimibe lowers low-density lipoprotein cholesterol (LDL-C) by 15-20% when used alone2 as compared to 5-10% from doubling the dose of statin.
What foods should be avoided when taking ezetimibe?
Grapefruit Juice: Ezetimibe interacts with grapefruit juice. Grapefruit juice increases the drug levels in the blood stream potentially leading to side effects of the drug.
What is the side effect of Nexletol?
| Adverse Reaction | NEXLETOL + Statin and ± Other Lipid Lowering Therapies (N = 2009) % | Placebo (N = 999) % |
|---|---|---|
| Muscle spasms | 3.6 | 2.3 |
| Hyperuricemiaa | 3.5 | 1.1 |
| Back pain | 3.3 | 2.2 |
| Abdominal pain or discomfortb | 3.1 | 2.2 |
Does Nexletol cause high blood pressure?
Nexletol (bempedoic acid) does not cause high blood pressure (hypertension) as a side effect according to the manufacturer’s package insert. However, in a clinical study, more people taking Nexletol (4.3%) had a report of hypertension compared to those on placebo (1.8%).
What are the most common side effects of ezetimibe?
Common side effects may include:
- muscle or joint pain;
- stuffy nose, sinus pain, sore throat;
- diarrhea; or.
- pain in an arm or leg.
Can ezetimibe cause weight gain?
Bottom line: Ezetimibe does not cause weight gain or weight loss.
What can I take instead of statin?
7 cholesterol-lowering alternatives to statins
- Fibrates. Mostly used for lowering triglyceride levels in patients whose levels are very high and could cause pancreatitis.
- Plant stanols and sterols.
- Cholestyramine and other bile acid-binding resins.
- Niacin.
- Policosanol.
- Red yeast rice extract (RYRE)
- Natural products.
