What is FlyBase used for?
Table of Contents
What is FlyBase used for?
FlyBase can be searched for genes, alleles, aberrations and other genetic objects, phenotypes, sequences, stocks, images and movies, controlled terms, and Drosophila researchers using the tools available from the ‘Tools’ drop-down menu in the Navigation bar.
What is genome browser used for?
Genome browsers integrate genomic sequence and annotation data from different sources and provide a platform to search, browse, retrieve, and analyze genomic data.
Who created FlyBase?
The FlyBase project is carried out by a consortium of Drosophila researchers and computer scientists at Harvard University and Indiana University in the United States, and University of Cambridge in the United Kingdom.
Which type of database is FlyBase?
relational database
FlyBase is a database of genetic and molecular data concerning Drosophila . FlyBase is maintained as a relational database (in Sybase). The scope of FlyBase includes: genes, alleles (and phenotypes), aberrations, pointers to sequence data, clones, stock lists, Drosophila workers and bibliographic references.
What are genome browser tracks?
Genome Browser annotation tracks are based on files in line-oriented format. Each line in the file defines a display characteristic for the track or defines a data item within the track. Annotation files contain three types of lines: browser lines, track lines, and data lines.
Why do isoforms exist?
Protein isoforms – proteins that are similar to each other and perform similar roles within cells – have played an important role in the generation of biological diversity throughout evolution. In some cases a single gene can encode two or more isoforms by exploiting a process called alternative splicing.
How many isoforms does a gene have?
These isoform genes are widely distributed among human chromosomes and the encoded enzymes share amino acid sequence homology (Table 1). Based on the sequence homology, the nine isoforms can be classified into four groups, 1–4 (Fig. 3).
What is a human ortholog?
Orthologs are genes which evolved from a common ancestral gene by speciation that usually have retained a similar function in different species. Paralogs are genes related by duplication within the genome and often they acquire a new function.
Is FlyBase primary database?
Abstract. FlyBase ( http://flybase.org ) is the primary database of integrated genetic and genomic data about the Drosophilidae, of which Drosophila melanogaster is the most extensively studied species.
What are tracks in Genome Browser?
How do you read a genomic location?
The position is usually designated by two digits (representing a region and a band), which are sometimes followed by a decimal point and one or more additional digits (representing sub-bands within a light or dark area). The number indicating the gene position increases with distance from the centromere.
How do I read a genome browser?
To open the Genome Browser window:
- Select the clade, genome and assembly that you wish to display from the corresponding pull-down menus.
- Specify the genome location you’d like the Genome Browser to open to.
- Click the submit button to open up the Genome Browser window to the requested location.
