What is normal SUV on PET scan?

What is normal SUV on PET scan?

Positron Emission Tomography Typically, a standardized uptake value (SUV), a quantity that incorporates the patient’s size and the injected dose, that is more than 2.0 is considered to be suggestive of malignancy, whereas lesions with SUVs less than this value are considered to be benign.

What does maximum SUV mean on PET scan?

The maximum standardized uptake value (SUVmax) is widely used for measuring the uptake of FDG by malignant tissue (Gambhir 2002). Increased FDG uptake values reflect the viability of cancer cells, and can be imaged and quantified using PET.

What does an SUV of 2.5 mean on a PET scan?

An SUV of 2.5 or higher is generally considered to be indicative of malignant tissue; however, there has been a wide range of SUVs reported for similar diseases. Table 4-2 summarizes some of these reported values. 74. It is important to recognize that an SUV around 2.5 can be measured in non-malignant regions.

What is normal SUV in lymph nodes?

The median SUVmax values of pathologically negative and positive lymph nodes were 1.6 (range, 0.4–11.3) and 5.4 (range, 1.1–17.8), respectively (Figure 1).

What is a normal SUV max?

The average normal SUVmax values from 11 patients were: cervical vertebrae 6.84 (range 4.38–8.64), thoracic vertebrae 7.36 (range 6.99–7.66), lumbar vertebrae 7.27 (range 7.04–7.72), femoral head 2.22 (range 1.1–4.3), humeral head 1.82 (range 1.2–2.9), mid sternum 5.51 (range 2.6–8.1), parietal bone 1.71 (range 1.3–2.4 …

How is SUV calculated?

In FDG studies SUV can be corrected for plasma glucose level, because glucose transporters may be saturated by glucose. SUV is multiplied by plasma glucose concentration / 5.0 (where 5.0 represents the population average of plasma glucose concentration).

What is normal SUV max for lung?

A weighted average calculation including the data from two previously published studies from other labs show the average mean SUV of normal lung parenchyma to be 0.52 (n=279).

What is maximum SUV?

Objectives: Maximum standardized uptake value (SUV(max)) is a marker of tumor glucose metabolism detected by [(18)F]-fluorodeoxyglucose ((18)F-FDG) PET/computed tomography (PET/CT) and reflects tumor aggressiveness.

What is SUV in lymphoma?

The majority of transformed lymphomas have high standardized uptake values (SUVs) on positron emission tomography (PET) scanning similar to diffuse large B-cell lymphoma (DLBCL)

What is SUVmax range?

Median SUVmax values of grade 1, 2 and 3 were 5.7 (range 2.1-18.2), 9.5 (range 2.2-21.3), and 11.6 (range 3.5-23), respectively.

What is a normal liver SUV?

Results: Normal Gaussian distributions of mean SUV changes. for liver and blood pool were obtained. Mean SUVmax and SUVmean. values for liver were 2.73±0.22 and 2.34±0.16, respectively, and 1.80±0.2 and 1.57±0.14 for blood pool, respectively.

What is a normal mediastinal blood pool SUV?

Conclusion: In our patient cohort, the reference range for intrapatient variation in blood-pool and liver SUVs is -0.8 to 0.9 and -0.9 to 1.1, respectively.

What does maximum SUV mean?

Maximum Standard Unit Value (SUVmax) is an indicator for overall survival in lung cancer.

What is the normal SUV of the liver?

The SUVmean values were 2.44 ± 0.40, 2.47 ± 0.37, 2.23 ± 0.42, and 2.01 ± 0.36, in the hepatic steatosis group, chronic hepatitis group, control group, and cirrhosis group, respectively, and statistical differences were observed between any two groups except for steatosis and hepatitis groups.

What does high SUV max mean?

Conclusion: Patients with early cervical cancer showing a high SUVmax (>or=13.4) of the cervical tumor should be considered at increased risk for disease recurrence after surgery and may need more aggressive multimodal treatment.