What is the use of allopurinol drug?

What is the use of allopurinol drug?

Allopurinol is a medicine used to lower levels of uric acid in your blood. If you produce too much uric acid or your kidneys do not filter enough out, it can build up and cause tiny, sharp crystals to form in and around your joints. Allopurinol is used to treat gout and kidney stones.

What drug can replace allopurinol?

Febuxostat, a novel nonpurine selective inhibitor of xanthine oxidase, is a potential alternative to allopurinol for patients with hyperuricemia and gout.

What type of drug is allopurinol?

Allopurinol is in a class of medications called xanthine oxidase inhibitors. It works by reducing the production of uric acid in the body. High levels of uric acid may cause gout attacks or kidney stones. Allopurinol is used to prevent gout attacks, not to treat them once they occur.

What are the side effects of allopurinol to the kidneys?

Allopurinol oral tablet is used to treat gout, elevated serum uric acid levels, and recurrent kidney stones….Allopurinol side effects

• skin rash.
• diarrhea.
• nausea.
• changes in your liver function test results.
• gout flare-up (if you have gout)

When is the best time to take allopurinol?

Allopurinol is taken as a tablet once a day. It is usually better to take it just after eating and the tablet should be swallowed with water. It is important to drink plenty of water during the day because this will help you get rid of more urate through your kidneys.

Does allopurinol have side effects?

Stomach upset, nausea, diarrhea, or drowsiness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects.

Can allopurinol raise blood pressure?

A meta-analysis of the effect of allopurinol on BP, combining data from 10 clinical studies with 738 participants, found a small reduction in BP in allopurinol-treated patients (3.3 mm Hg; 95% confidence interval [CI], −1.4 to −5.3 mm Hg) for systolic BP.

What medicines should not be taken with allopurinol?

Serious Interactions of Allopurinol include:

• azathioprine.
• benazepril.
• captopril.
• didanosine.
• dyphylline.
• enalapril.
• perindopril.
• protamine.

Can allopurinol cause heart problems?

Yet another study of gout patients using Scottish database reported that compared to non-use, allopurinol use was associated with higher (not lower) adjusted hazards of cardiovascular hospitalization (including coronary artery disease (CAD), hypertensive heart disease, heart failure, stroke, other cardiovascular …