Why do pregnant patients require special dosing?
Table of Contents
Why do pregnant patients require special dosing?
Absorption, distribution, metabolism and excretion of drugs may be affected by the physiological changes that occur during pregnancy. These factors may in turn impact on the drug dose needed by the pregnant woman (2).
Which is the safest antihypertensive drug to be used in pregnant ladies?
The drugs most commonly used—methyldopa, labetalol, and nifedipine—are widely accepted as safe in pregnancy, based on many years of experience, observational data from large databases, and meta‐analyses of multiple small clinical trials.
Can domperidone be given in pregnancy?
Pregnancy and breastfeeding Domperidone is not usually recommended in pregnancy.
Should all medicine be avoided during pregnancy?
This means that even a woman who strictly avoids drugs and medications while pregnant may still have a baby with a birth defect. Most medicines are not harmful to a developing baby. However, some may interfere with the normal development of a fetus and cause birth defects (these medicines are said to be ‘teratogenic’).
Is amlodipine safe in pregnancy?
Amlodipine can be used in pregnancy. Although there is not a lot of information on its safety, it is not thought to be harmful to the baby. If you are pregnant, or planning a pregnancy, talk to your doctor about it. They may wish to change amlodipine for a medicine that has more safety information.
What is first line treatment for hypertension in pregnancy?
Background: Hydralazine, labetalol, and nifedipine are the recommended first-line treatments for severe hypertension in pregnancy.
What is Category C drugs in pregnancy?
Category C: Studies in animals have revealed adverse effects on the fetus and there are no controlled studies in women, or studies in women and animals are not available. Drugs from this class can be given to pregnant women if the benefit to the mother outweighs the risk to the fetus.
Can Stemetil be used in pregnancy?
Like most phenothiazine medicines, Stemetil is not recommended for use during pregnancy. If there is a need Page 2 STEMETIL® 2 to take Stemetil during your pregnancy, your doctor will discuss with you the benefits and risks of using it. Tell your doctor or pharmacist if you are breastfeeding or plan to breastfeed.
How is hypertension treated during pregnancy?
There are a wide variety of agents available for use, and orally administered antihypertensive agents can be used in standard doses in pregnancy (Table 2). First-line agents for nonsevere hypertension are methyldopa and labetalol, with nifedipine as second line, followed by others in third line.
