How do you dilute Cytarabine?

How do you dilute Cytarabine?

Dilution of Conventional Cytarabine Cytarabine injection solution (containing 20 or 100 mg/mL) may be diluted with a compatible IV solution (e.g., 5% dextrose injection, 0.9% sodium chloride injection) for direct IV injection, rapid IV injection, or IV infusion.

How do you administer IV Cytarabine?

Cytarabine, under strict medical surveillance, is administered as monotherapy or in combination with other cytostatics, 2-3 g/m2, as intravenous infusion, for 1-3 hours every 12 hours for 2-6 days. (Total of 12 doses per cycle). A total treatment dose of 36 g/m2 should not be exceeded.

How does Ara C work?

How it works. Cytarabine is a type of chemotherapy drug. It kills cancer cells by stopping them from making and repairing DNA that they need to grow and multiply.

How do you infuse cyclophosphamide?

Cyclophosphamide should be prepared for parenteral use by infusion by adding Sterile Water for Injection, USP. Cyclophosphamide, constituted in water, is hypotonic and should not be injected directly. Add the diluent to the vial and shake it vigorously to dissolve.

How do you give cytarabine subcutaneous injection?

The needle will deliver the injection just below the skin. Once the needle is in place release the pinch on the skin if you need both hands. into the sharps bin and place the tissue on your skin firmly over the injection site.

What are ARA medications?

ARA-II: Angiotensin II receptor antagonists (ARA-II) belong to a recent class of antihypertensive drugs whose mechanism of action is similar to converting enzyme inhibitors (CEI).

How do you use cyclophosphamide injection?

Cyclophosphamide injection comes as a powder to be added to fluid and injected intravenously (into a vein) by a doctor or nurse in a medical office or hospital outpatient clinic.

How do you give Cytarabine?

Intermittent dosing: Cytarabine may be given as intermittent intravenous doses of 3-5 mg/kg daily, for five consecutive days. This course of treatment can be repeated after an interval of 2 to 9 days and repeated until the therapeutic response or toxicity is exhibited.

What is the 7 3 regimen?

This is sometimes called a 7 + 3 regimen, because it consists of getting cytarabine continuously for 7 days, along with short infusions of an anthracycline on each of the first 3 days.

What are MRA drugs?

Aldosterone receptor antagonists, also called MRAs, block the effects of a hormone produced naturally by your adrenal glands which can cause your heart failure to get worse. Aldosterone receptor antagonists affect the balance of water and salts going into your urine and are weak diuretics.

How do you administer cyclophosphamide orally?

Cyclophosphamide can be given by intravenous (IV, into a vein) infusion or taken orally (by mouth) in a pill or capsule form. This information is about the oral (by mouth) formulation. Oral doses should be taken whole (not crushed, chewed, or broken) and with food in order to decrease nausea.