How is Aranesp dosed?
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How is Aranesp dosed?
The recommended starting dose is 0.45 mcg/kg intravenously or subcutaneously as a weekly injection or 0.75 mcg/kg once every 2 weeks as appropriate. The intravenous route is recommended for patients on hemodialysis.
How often can Aranesp be given?
Aranesp is administered less frequently than epoetin alfa. Administer Aranesp once weekly in patients who were receiving epoetin alfa 2 to 3 times weekly. Administer Aranesp once every 2 weeks in patients who were receiving epoetin alfa once weekly.
How do you give Aranesp IV?
Aranesp can be injected directly into a layer of fat under your skin. This is called a subcutaneous injection. When giving subcutaneous injections, follow your healthcare provider’s instructions about changing the site for each injection. You may wish to write down the site where you have injected.
Is darbepoetin alfa the same as Aranesp?
No, Aranesp (darbepoetin alfa) is not the same as Procrit (epoetin alfa), but they do belong to the same drug class and work well to treat certain anemias. A major difference is that Aranesp (darbepoetin alfa) lasts longer and doesn’t need to be injected as often.
What is another name for Aranesp?
Aranesp is the trade name for darbepoetin alfa. In some cases, health care professionals may use the trade name aranesp when referring to the generic drug name darbepoetin alfa. Drug Type: Darbepoetin alfa is a biologic response modifier. It is an erythropoiesis stimulating protein.
What classification is Aranesp?
Darbepoetin alfa is in a class of medications called erythropoiesis-stimulating agents (ESAs). It works by causing the bone marrow (soft tissue inside the bones where blood is made) to make more red blood cells.
How long does Aranesp last?
It is typically administered every two weeks, allowing patients to visit their doctor less frequently and avoid unnecessary injections.
Can Aranesp cause kidney failure?
Aranesp may sometimes cause or worsen high blood pressure, especially in patients with long-term kidney failure….Table 5. Adverse Reactions Occurring in ≥ 5% of Patients with CKD.
| Adverse Reaction | Patients Treated with Aranesp (n = 766) |
|---|---|
| Hypertension | 31% |
| Dyspnea | 17% |
| Peripheral edema | 17% |
| Cough | 12% |
Can Aranesp be self administered?
Use these instructions if you or your caregiver has been trained to give Aranesp injections at home. Do not give yourself the injection unless you have received training from your healthcare provider. If you are not sure about giving the injection or if you have questions, ask your healthcare provider for help.
How often is darbepoetin given?
It is usually injected once every 1 to 4 weeks. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use darbepoetin alfa injection exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.
What is the cost of Aranesp injection?
The cost for Aranesp injectable solution (25 mcg/mL) is around $825 for a supply of 4 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What happens if you take too much Aranesp?
Using Aranesp can lead to death or other serious side effects. You may get serious heart problems such as heart attack, stroke, heart failure, and may die sooner if you are treated with Aranesp to reach a normal or near-normal hemoglobin level.
Can you overdose on Aranesp?
Yes, like many other drugs, the anemia drug darbepoetin alfa (Aranesp) can be overdosed, which could be very dangerous. If you think an overdose has occurred with darbepoetin alfa, call the Poison Control Center at 1-800-222-1222 immediately. In the case of an overdose, you might have some severe side effects.
Does Aranesp make you tired?
Tell your doctor right away if you have any serious side effects, including: symptoms of heart failure (such as shortness of breath, swelling ankles/feet, unusual tiredness, unusual/sudden weight gain). Get medical help right away if you have any very serious side effects, including: seizures.
Does Aranesp help kidney function?
Some people are able to be more active. But darbepoetin alfa only corrects anemia. It has no effect on kidney disease, cancer, or any other medical problem that needs regular medical attention.
How long does it take for Aranesp to start working?
Aranesp® “tells” the cells in your bone marrow to grow into new red blood cells within your bloodstream. Under healthy circumstances, it takes your body time to produce red blood cells (about 26 days 3,4,5,6). Increases in hemoglobin may not be observed until 2-6 weeks after you start taking Aranesp®.
How much does Aranesp cost?
About Aranesp It is used to treat anemia caused by chronic kidney failure and chemotherapy. The lowest GoodRx price for the most common version of Aranesp is around $759.98, 17% off the average retail price of $925.49. Compare erythropoiesis-stimulating agents.
