What is erlotinib used for?

What is erlotinib used for?

Erlotinib is used for the treatment of metastatic (cancer that has already spread) non-small cell lung cancer in patients who have certain types of abnormal epidermal growth factor (EGFR) gene mutations. Your doctor will perform a test before you take this medicine.

What is the most common side effect of erlotinib?

The most common adverse reactions with TARCEVA are rash and diarrhea usually with onset during the first month of treatment. The incidences of rash and diarrhea from clinical studies of TARCEVA for the treatment of NSCLC and pancreatic cancer were 70% for rash and 42% for diarrhea.

What is the mechanism of action of erlotinib?

Mechanism of Action and Pharmacodynamics Erlotinib inhibits the intracellular phosphorylation of tyrosine kinase associated with the epidermal growth factor receptor (EGFR). Specificity of inhibition with regard to other tyrosine kinase receptors has not been fully characterized.

Can erlotinib cure lung cancer?

Erlotinib at the standard oral daily dose of 150mg is approved for the treatment of unselected chemorefractory advanced non-small cell lung cancer patients as well as maintenance therapy after first-line chemotherapy.

Is erlotinib a chemotherapy?

Erlotinib is a type of targeted cancer drug, and is also known by its brand name Tarceva (pronounced tar-see-vah). It is a treatment for: non small cell lung cancer (NSCLC) that has spread (advanced) advanced pancreatic cancer – alongside the chemotherapy drug gemcitabine.

How long does erlotinib take to work?

Erlotinib is highly effective in the subset of patients carrying EGFR mutations. However, even these patients will eventually begin to show progression of their cancer after about 12 months of erlotinib therapy.

Is erlotinib a chemotherapy drug?

Can Stage 4 lung cancer be put into remission?

Complete remission of advanced NSCLC can be achieved using the combination of oral icotinib and BAI chemotherapy. Core tip: Few patients can undergo surgery for treatment of non-small-cell lung cancer because of advanced disease or poor pulmonary function.

How much does erlotinib cost?

The cost for erlotinib oral tablet 25 mg is around $1,388 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

What is the cost of erlotinib?

Is erlotinib still used?

Tarceva (erlotinib) is widely used in the management of EGFR + non-small cell lung cancer (NSCLC) and clinical studies suggests it improves survival in early stage disease, as part of initial treatment for stage IV NSCLC, as maintenance therapy and in select individuals with recurrent disease.

Who makes erlotinib?

Genentech: Tarceva® (erlotinib) – Information for Patients.

How expensive is Tarceva?

The cost for Tarceva oral tablet 25 mg is around $2,874 for a supply of 30 tablets, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans. A generic version of Tarceva is available, see erlotinib prices.

Is there a generic for Tarceva?

The generic drug erlotinib comes as the brand-name version, Tarceva.

How long has Tarceva been on the market?

On November 18, 2004, erlotinib (Tarceva); OSI Pharmaceuticals, Inc., Melville, NY, http://www.osip.com, and Genentech, Inc., South San Francisco, CA, http://www.gene.com) received regular approval as monotherapy for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) after …