What is podophyllotoxin used for?
Table of Contents
What is podophyllotoxin used for?
Podophyllotoxin☆ It is used on the skin as a topical treatment of external genital warts, caused by some types of the human papillomavirus (HPV), and other warts. It also has a variety of medical applications such as purgative, vesicant, antirheumatic, antiviral, and antitumor agents.
What is Podofilox made from?
Podofilox (podophyllotoxin) is a biologically active component in podophyllum resin, a crude extract from the roots and rhizomes of the May apple or podophyllum plant (either the North American Podophyllum peltatum or the Indian Podophyllum emodi).
What is biological source of podophyllotoxin?
Podophyllotoxin is present at concentrations of 0.3% to 1.0% by mass in the rhizome of the American mayapple (Podophyllum peltatum). Another common source is the rhizome of Sinopodophyllum hexandrum Royle (Berberidaceae).
Is podophyllin an antibiotic?
Podophyllin is a cytotoxic agent that has been used topically in the treatment of genital warts. It arrests mitosis in metaphase, an effect it shares with other cytotoxic agents such as the vinca alkaloids.
Can I use podophyllin everyday?
Adults and children—Apply to the affected area(s) of the skin and leave on the skin for one to six hours. Treatment may be repeated every week for up to six weeks.
What is the difference between podophyllin and podophyllotoxin?
Podophyllotoxin is standardised and stable, whereas podophyllin has a variable composition. In an open comparison of self applied podophyllotoxin 0.5% versus podophyllin 20% applied by a doctor to treat external penile warts, podophyllotoxin was more effective and gave quicker resolution than podophyllin.
What are the side effects of podofilox?
Side Effects
- Bad odor (solution only)
- bleeding of treated skin.
- blistering, crusting, or scabbing of treated skin.
- bloody urine (solution only)
- burning feeling of treated skin.
- dizziness (solution only)
- headache (gel only)
- itching of treated skin.
How long does podophyllotoxin take to work?
It works best on softer fleshier warts than very hard warts. You would usually expect to see a difference in the first couple of weeks but may need more than one course of treatment.
Does podophyllin cure warts?
Podophyllum is used to remove benign (not cancer) growths, such as certain kinds of warts. It works by destroying the tissue of the growth. A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue.
How long does podophyllin take to remove warts?
It works by destroying the tissue of the growth. A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue. After about 72 hours, the wart begins to slough or come off and gradually disappears.
How long should podophyllin be applied?
What does podofilox do to warts?
Podofilox works by destroying the skin of the wart. This medicine is available only with your doctor’s prescription.
Can podophyllin remove skin tags?
How do I know podophyllin cream is working?
A few hours after podophyllum is applied to a wart, the wart becomes blanched (loses all color). In 24 to 48 hours, the medicine causes death of the tissue. After about 72 hours, the wart begins to slough or come off and gradually disappears.
Can podophyllin remove warts?
How many times can I use podofilox?
Use podofilox only as directed, no more than 3 days a week and no more than 4 treatment cycles. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.
How long is podofilox good for?
Typical dosing for podofilox (Condylox) Repeat this 1-week cycle until the wart is gone, and do not use for more than 4 cycles. If the wart isn’t gone after 4 treatment cycles, stop using and ask your provider for alternatives.
