What kind of nebulizer is used for Pulmozyme?

What kind of nebulizer is used for Pulmozyme?

Pulmozyme (dornase alfa) should only be used with the approved nebulizers and compressors or with the eRapid® Nebulizer System. Any other inhaled medicines should not be used in the nebulizer at the same time. Keep all other inhaled medication systems completely separate from Pulmozyme (dornase alfa).

How do you administer Pulmozyme?

Place the inhalation solution in the medicine reservoir or nebulizer cup on the machine. Connect the nebulizer to the face mask or mouthpiece, then connect the nebulizer to the compressor. Use the mouthpiece of the nebulizer to breathe in Pulmozyme®.

Why is Pulmozyme used in cystic fibrosis?

How Pulmozyme works to fight cystic fibrosis. Laboratory studies show that Pulmozyme (dornase alfa) cuts apart extracellular DNA by acting like an enzyme* naturally found in the lungs. By cutting this extracellular DNA, Pulmozyme helps make the thick, sticky mucus that your lungs produce thinner and looser.

When do you use Pulmozyme?

PULMOZYME® (dornase alfa) is indicated for daily administration in conjunction with standard therapies for the management of cystic fibrosis (CF) patients to improve pulmonary function.

Can you mix Pulmozyme and albuterol?

Pulmozyme should not be diluted or mixed with other medications. Do not use Pulmozyme if the solution is cloudy, discolored or left at room temperature for 24 hours. Pulmozyme should be given after a nebulized bronchodilator (such as albuterol) and before inhaled antibiotics (such as TOBI) if ordered.

What is hypertonic saline nebulizer used for?

What is hypertonic saline (HTS) nebulization? Hypertonic saline belongs to a class of drugs called mucolytics. It is a salty solution that helps to hydrate the airways and thin the mucus in the lungs. Hydrating the airways helps the respiratory tract move the mucus from the lungs.

How often is Pulmozyme taken?

The recommended dose for most CF patients is Pulmozyme 2.5 mg once-daily. Some patients over 21 may benefit from twice-daily treatment. You should ask your doctor whether prescribing Pulmozyme 2.5 mg twice-daily may be right for you.

Does Pulmozyme need to be given with a bronchodilator?

Pulmozyme should be given after a nebulized bronchodilator (such as albuterol) and before inhaled antibiotics (such as TOBI) if ordered.

How often is Pulmozyme given?

Pulmozyme is available for once- or twice-daily administration. The recommended dose for most patients with CF is 2.5 mg once daily (QD); however, some patients over 21 years of age may benefit from 2.5 mg twice-daily (BID) dosing to reduce exacerbation risk.

Can Pulmozyme be mixed with bronchodilator?

Does Pulmozyme have many adverse effects?

The most common adverse reactions associated with the use of Pulmozyme include: voice alteration, pharyngitis, rash, laryngitis, chest pain, conjunctivitis, rhinitis, decrease in FVC of ≥ 10%, fever, dyspepsia, and dyspnea. There have been no reports of anaphylaxis attributed to the administration of Pulmozyme.

What is the difference between hypertonic saline and normal saline?

Any solution of sodium chloride (NaCl) in water with a concentration of NaCl higher than that found in physiological saline (0.9% w/v).

Can you Nebulize hypertonic saline?

Nebulized hypertonic saline also reduced the risk of hospitalization by 20% compared with 0.9% saline (relative risk [RR] = 0.80; 95% CI, 0.67 to 0.96). No significant adverse events related to hypertonic saline inhalation were reported.

Why is Pulmozyme important?

Why is Pulmozyme an important part of my CF treatment? In CF, your lungs produce extra-thick, sticky mucus. Laboratory studies have shown that Pulmozyme works to help make mucus thinner and looser. You can learn more about the clinical data supporting the use of Pulmozyme.

How much does Pulmozyme cost?

The cost for Pulmozyme inhalation solution (2.5 mg/2.5 mL) is around $3,821 for a supply of 75 milliliters, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.

How long does it take for Pulmozyme to work?

This recommendation is based on evidence that Pulmozyme® makes CF sputum pourable within 30 minutes (Shak 1990).

Can you mix Dornase Alfa with albuterol?

CF patients often mix dornase alfa with bronchodilatators like ipratropium bromide (Atrovent® and Atrovent® Fertiginhalat) and albuterol (Sultanol® and Sultanol® forte Fertiginhalat).

Is isotonic or hypertonic better?

Scientific evidence has proven that when the salt comes in contact with your sinuses, it draws out the mucus and fluid more effectively than an isotonic saline would. Since hypertonic solutions are stronger than isotonic, they should be your go-to, particularly if your sinuses are more swollen than normal.

When should hypertonic saline be used?

Clinicians use hypertonic fluids to increase intravascular fluid volume. Hypertonic saline can be utilized in the treatment of hyponatremia. Hypertonic saline and mannitol are both indicated to reduce intracranial pressure.

Can you mix albuterol and saline in nebulizer?

Upon review of DP’s current nebulizer therapies, all medication (albuterol-ipratropium, budesonide, sodium chloride 0.9%) are compatible when mixed together, presenting an opportunity to combine treatments.