What time is best to take Vytorin?

What time is best to take Vytorin?

VYTORIN should be taken once a day, in the evening. The liver produces its greatest amount of cholesterol when the body is at rest and when there is no dietary intake. For most people this is at night when asleep. Therefore, VYTORIN is more effective when taken in the evening.

Why is Vytorin taken at night?

They act by inhibiting the enzyme HMG CoA reductase, which controls synthesis of cholesterol in the liver. Most manufacturers of statins recommend that they are taken at night, on the basis of physiological studies which show that most cholesterol is synthesised when dietary intake is at its lowest.

Does Vytorin cause memory loss?

Memory loss But simvastatin, one of the active drugs in Vytorin, is a statin. And problems with memory have been reported as a side effect of simvastatin as well as other statin drugs. Memory problems that occur when taking statins tend to be mild and may include: forgetfulness.

How long does it take Vytorin to lower cholesterol?

Most people with high cholesterol or triglycerides do not feel sick. It is very important to continue to follow your doctor’s advice about diet and exercise. It may take up to 4 weeks before you get the full benefit of this drug.

What are some of the side effects of Vytorin?

Common side effects of Vytorin include:

• headache,
• nausea,
• vomiting,
• diarrhea,
• dizziness,
• depression,
• memory problems,
• confusion,

Does Vytorin cause insomnia?

Researchers have found that fat-soluble statins — which include Lipitor, Mevacor, Vytorin and Zocor — are more likely to cause insomnia or nightmares because they can more easily penetrate cell membranes and make their way across the blood-brain barrier, which protects the brain from chemicals in the blood.

Can ezetimibe cause depression?

The reactions mentioned in these reports include depression, memory loss, confusion and aggressive reactions. Convincing reports to CARM of recurrence of these reactions upon rechallenge add weight to recent studies reporting serious psychiatric disturbances in association with statin treatment.

Is Vytorin a good statin?

Early findings from the study showed that Vytorin, which combines the unique cholesterol drug Zetia with the older, cheaper statin drug Zocor, was no better than Zocor alone at slowing plaque buildup in high-risk patients.

Does Vytorin make you sleepy?

fever, unusual tiredness; upper stomach pain, loss of appetite; dark colored urine; or. jaundice (yellowing of the skin or eyes).

Which statins must be taken at bedtime?

To maximize the effects of statins with a short half-life, fluvastatin, lovastatin, and simvastatin should be dosed at bedtime allowing the greatest drug concentration to be present during peak endogenous cholesterol synthesis.

What medications should not be taken with ezetimibe?

You should not use ezetimibe with a “statin” cholesterol medicine (Zocor, Lipitor, Crestor, and others) if:

• you have active liver disease;
• you are pregnant; or.
• you are breastfeeding a baby.

Does ezetimibe make you gain weight?

Ezetimibe does not cause weight gain or weight loss. Ezetimibe has a well documented safety profile. Ezetimibe has low risk for the side effect of muscle ache and pains.

Is Crestor better than Vytorin?

Vytorin reduced LDL, or “bad” cholesterol, by 52 to 61 percent, depending on the dosage, compared to reductions of 46 to 57 percent for comparable doses of Crestor, according to the study, which was conducted by independent researchers and funded by Merck and Schering-Plough.

Why am I gaining weight on statins?

Statin use is associated with increased calorie intake and consequent weight gain. It is speculated that statin‐dependent improvements in lipid profile may undermine the perceived need to follow lipid‐lowering and other dietary recommendations leading consequently to increased calorie intake.