What type of cancer is dermatofibrosarcoma protuberans?
Table of Contents
What type of cancer is dermatofibrosarcoma protuberans?
Dermatofibrosarcoma protuberans (DFSP) is a rare type of skin cancer. It starts in connective tissue cells in the middle layer of the skin (dermis). Dermatofibrosarcoma protuberans might look like a pimple or feel like a rough patch of skin at first.
Is dermatofibrosarcoma protuberans benign?
DFSP is considered an intermediate tumor between a benign dermatofibroma and a frank fibrosarcoma due to the possibility of having distant metastasis and aggressive local invasion. Transformation to a high-grade sarcoma is extremely rare.
Does dermatofibrosarcoma protuberans metastasis?
Dermatofibrosarcoma protuberans (DFSP) is a tumor that develops in skin or subcutaneous tissue and is characterized by a protuberant growth pattern [1]. DFSP often recurs locally after surgery, but rarely metastasizes to distant sites and is classified as a sarcoma of intermediate-grade malignancy [2–7].
How long can you live with sarcoma cancer?
5-year relative survival rates for soft tissue sarcoma
| SEER Stage | 5-Year Relative Survival Rate |
|---|---|
| Localized | 81% |
| Regional | 56% |
| Distant | 15% |
| All SEER stages combined | 65% |
Is dermatofibrosarcoma protuberans fatal?
Background: Dermatofibrosarcoma protuberans (DFSP) is an uncommon intermediate-grade fibrohistiocytic sarcoma. It occurs most often in adults aged 20-50 years and is associated with local invasion and a high recurrence rate. Uncontrolled local disease or metastases may result in death.
Who gets dermatofibrosarcoma protuberans?
DFSP tends to affect people between the age of 20 and 50, but it has been diagnosed in people of all ages. There are about 1,000 cases diagnosed in the United States each year, with an incidence of about 1-5 people per million. The tumors affect black patients about twice as much as white patients.
Is dermatofibroma benign or malignant?
Dermatofibroma (cutaneous fibrous histiocytoma) represents a common benign mesenchymal tumor, and numerous morphological variants have been described. Some variants of dermatofibroma are characterized by an increased risk of local recurrences, and there are a few reported metastasizing cases.
How do you get dermatofibrosarcoma protuberans?
Dermatofibrosarcoma protuberans results from a new mutation that occurs in the body’s cells after conception and is found only in the tumor cells. This type of genetic change is called a somatic mutation and is generally not inherited.
Is a dermatofibroma a tumor?
Cellular dermatofibromas are a type of dermatofibroma (noncancerous tumor). They appear as firm bumps (nodules), often on your legs.
Is dermatofibrosarcoma protuberans painful?
When dermatofibrosarcoma protuberans (DFSP) first appears on the skin, a person may notice: A pimple-like growth or rough patch of skin. No pain or tenderness where the growth or patch forms.
How do you get dermatofibroma?
Dermatofibromas are caused by an overgrowth of a mixture of different cell types in the dermis layer of the skin. The reasons why this overgrowth occurs aren’t known. The growths often develop after some type of small trauma to the skin, including a puncture from a splinter or bug bite.
