Can nitrofurantoin cause lung problems?

Can nitrofurantoin cause lung problems?

Nitrofurantoin is known to cause both acute and chronic pulmonary reactions. Interstitial lung disease and pulmonary fibrosis may develop with long-term use. Patients on prolonged nitrofurantoin therapy should be monitored for lung function changes and nitrofurantoin discontinued at the first signs of damage.

Can nitrofurantoin cause respiratory infection?

A high index of suspicion for an adverse drug reaction is warranted when patients taking nitrofurantoin experience respiratory symptoms and pulmonary infiltrates. If nitrofurantoin-induced lung injury is suspected, re-exposure to nitrofurantoin therapy should be avoided.

How does nitrofurantoin cause pulmonary toxicity?

The most likely cause of pulmonary complications of nitrofurantoin therapy is a hypersensitivity reaction [5]. The interstitial pneumonitis induced by nitrofurantoin is now classified as a non-cytotoxic pneumonitis. Non-cytotoxic drugs, including nitrofurantoin, can activate lymphocytes.

Can nitrofurantoin cause shortness of breath?

o If prescribing nitrofurantoin for cystitis treatment, instruct patient to report fever, change in breathing, more shortness of breath or cough.

Can Macrobid affect your breathing?

This medication may rarely cause very serious (possibly fatal) lung problems. Lung problems may occur within the first month of treatment or after long-term use of nitrofurantoin (generally for 6 months or longer).

Can nitrofurantoin cause pleurisy?

Nitrofurantoin has been documented as a cause of acute, sub-acute, and chronic pulmonary injury. This is a case of an 82 year-old female who presented with multiple episodes of respiratory symptoms due to recurrent pleural effusions after beginning nitrofurantoin therapy for urinary tract infection prophylaxis.

Does nitrofurantoin cause cough?

Introduction. Nitrofurantoin is used to treat uncomplicated urinary tract infection, and its use can lead to acute, subacute, or chronic pulmonary toxicity [1]. Nitrofurantoin-associated pulmonary toxicity can manifest as cough, mild fever, shortness of breath, and pulmonary infiltrates on clinical imaging [2-7].

Can Macrobid make you short of breath?

shortness of breath, cough, fever or chills, numbness or tingling in the hands or feet, or.

Can nitrofurantoin affect asthma?

Two cases of probable nitrofurantoin (Furadantin) allergy, with associated acute asthma, are presented. Allergy to nitrofurantoin is reported infrequently. The relevant literature on this subject is briefly reviewed. While nitrofurantoin sensitivity appears to be rare, it is perhaps more common than is appreciated.

Can Macrobid cause chest pain?

Acute pulmonary reactions were commonly manifested by fever, chills, cough, chest pain, dyspnea, pulmonary infiltration with consolidation/pleural effusion on chest x-ray, and eosinophilia.

Can nitrofurantoin cause pleural effusion?

Is Macrobid good for upper respiratory infection?

This medication is an antibiotic used to treat bladder infections (acute cystitis). It works by stopping the growth of bacteria. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).

Can nitrofurantoin make you feel ill?

Nausea, flatulence, and headache are the most common nitrofurantoin side effects. Diarrhea is another common side effect that usually goes away after nitrofurantoin is discontinued. However, ongoing diarrhea that occurs up to two months after stopping the medication requires medical attention.

Can Macrobid cause shortness of breath?

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Is Macrobid good for pneumonia?

Macrobid (nitrofurantoin monohydrate/macrocrystals) and Augmentin (amoxicillin/clavulanate) are antibiotics used to treat urinary tract and bladder infections. Augmentin is also used to treat other bacterial infections including sinusitis, pneumonia, ear infections, bronchitis, and infections of the skin.