How is novocaine synthesized?

How is novocaine synthesized?

Procaine, the 2-diethylaminoethyl ester of 4-aminobenzoic acid (2.1. 1), better known as novocaine, is synthesized in two ways. The first way consists of the direct reaction of the 4-aminobenzoic acid ethyl ester with 2-diethylaminoethanol in the presence of sodium ethoxide.

How is procaine manufactured?

Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol.

How is Alcaine supplied?

ALCAINE (proparacaine hydrochloride ophthalmic solution) (Proparacaine Hydrochloride) Ophthalmic Solution. 0.5% is supplied in 15 mL DROP-TAINER® dispensers.

What is Novocaine made from?

Novocain, procaine hydrochloride, is benzoic acid, 4-amino-, 2-(diethylamino) ethyl ester, monohydrochloride, the ester of diethylaminoethanol and aminobenzoic acid, with the following structural formula: It is a white crystalline, odorless powder that is freely soluble in water, but less soluble in alcohol.

What is Novocaine derived?

Novocaine (or novocain), also known as procaine hydrochloride, is a local anesthetic that is commonly used during dental procedures, like cavity fillings. The Indian Dental Association mention that Lidocaine and novocaine are cocoa plant (erythroxylum coca) derivative and therefore safe.

What is the chemical name of procaine?

Procaine

Clinical data
Identifiers
IUPAC name 2-(diethylamino)ethyl 4-aminobenzoate
CAS Number 59-46-1
PubChem CID 4914

What is the chemical formula of procaine?

C13H20N2O2Procaine / Formula

Can you buy eye numbing drops over the counter?

Eye numbing drops are not available over the counter. These drops should only be applied under the supervision of a medical professional to avoid serious side effects and, in some cases, chemical dependency.

What do dentists use instead of Novocaine?

”In recent years, newer local anesthetics have been used instead of Novocaine, including lidocaine (Xylocaine) and articaine.”

What are the ingredients in Novocaine?

Novocain Description It is a white crystalline, odorless powder that is freely soluble in water, but less soluble in alcohol. Each mL contains 100 mg procaine hydrochloride and 4 mg acetone sodium bisulfite as antioxidant.

What plant is Novocaine made from?

What is procaine structure?

What are the functional groups in procaine?

This entity has been manually annotated by the ChEBI Team. Procaine is a local anesthetic drug of the amino ester group….CHEBI:8430.

Synonyms Sources
β-(diethylamino)ethyl p-aminobenzoate NIST Chemistry WebBook
novocaine ChEBI
p-Aminobenzoic acid 2-diethylaminoethyl ester ChemIDplus

How long does Proxymetacaine last?

Proxymetacaine hydrochloride is a rapid acting local anaesthetic suitable for ophthalmic use. With a single drop, the onset of anaesthesia usually begins within 30 seconds and persists for 15 minutes or longer.

  • October 5, 2022