What are the contraindications of atorvastatin?
Table of Contents
What are the contraindications of atorvastatin?
Contraindications
- Hypersensitivity to atorvastatin.
- Active liver disease or unexplained transaminase elevation.
- Your doctor should not prescribe this medication if you are a patient with liver problems.
- Women who are pregnant or breastfeeding should not take atorvastatin.
Can atorvastatin cause high blood pressure?
BP-lowering effects of atorvastatin were consistent in both daytime and nighttime periods. This study shows a mild, but consistent throughout the 24-h period BP-lowering effect of atorvastatin in patients with mild hypertension and hypercholesterolaemia.
Can I take atorvastatin with blood pressure medication?
Researchers say prescribing statins along with blood pressure medications improves the survival odds for people with hypertension. The number of deaths from stroke and heart disease could significantly decrease if people are given statins in combination with medications that lower blood pressure.
When are statins contraindicated?
Statins are contraindicated for use by patients with active hepatic disease or unexplained persistent elevations in aminotransferase levels. Statins are contraindicated during pregnancy and while breastfeeding because of the effects on the cholesterol pathway.
What should you check before administering atorvastatin?
Assess any muscle pain, tenderness, or weakness, especially if accompanied by fever, malaise, and dark-colored urine. Advise patient that these symptoms may represent drug-induced myopathy, and that myopathy can progress to severe muscle damage (rhabdomyolysis).
Do you take statins for high blood pressure?
“We found that statins lower both systolic and diastolic blood pressure, and that the effect extends to patients with pre-hypertension, with normal blood pressure, and persons not on blood-pressure lowering medications,” according to a news release from study researcher Beatrice Golomb, MD, PhD.
What drugs are contraindicated with statins?
Certain drugs can interact with atorvastatin (Lipitor) and increase its side effects. These include fibrates, niacin supplements, cyclosporine, clarithromycin, itraconazole, HIV protease inhibitors, oral contraceptives containing norethindrone or ethinyl estradiol, digoxin, rifampin, and colchicine.
Can statins lower blood pressure?
Conclusion: Statins lower blood pressure by cholesterol-independent mechanisms, and the reduction is larger in individuals with higher blood pressure and those with low HDL-C. Statins may be beneficial in preventing hypertension and may contribute to better blood pressure control in hypertensive patients.
What are nursing considerations for Lipitor?
Assess for signs of renal impairment. atorvastatin can increase liver enzyme levels….Nursing Diagnosis for Atorvastatin.
| Nursing Interventions for Atorvastatin | Rationales |
|---|---|
| Advise the patient to stop alcohol consumption while on atorvastatin. | This will prevent unwanted effects on the liver while on atorvastatin. |
Can statins cause blood pressure to rise?
Objective: As a class of cholesterol-lowering drugs, statins have been reported to cause unexpected decrease in blood pressure (BP).
Can statins raise blood pressure?
What should I check before giving atorvastatin?
Is high cholesterol linked to high blood pressure?
High blood pressure (hypertension) and high cholesterol are linked. Cholesterol plaque and calcium cause your arteries to become hard and narrow. So, your heart has to strain much harder to pump blood through them. As a result, your blood pressure becomes too high.
Can you take cholesterol medication with high blood pressure?
Combining drugs that lower blood pressure and cholesterol could do more to prevent stroke. Study Highlights: Combining medication that lowers blood pressure with medication that lowers cholesterol reduced first-time strokes by 44 percent.
What drugs does atorvastatin interact with?
Does high cholesterol cause high BP?
What should be monitor before giving atorvastatin?
Evaluate serum cholesterol and triglyceride levels before initiating, after 2–4 wk of therapy, and periodically thereafter.
- Monitor liver function tests prior to initiation of therapy and as clinically indicated.
- If patient develops muscle tenderness during therapy, CPK levels should be monitored.
