What is a PHEO crisis?
Table of Contents
What is a PHEO crisis?
Introduction. Pheochromocytoma crisis (PC) is a rare life-threatening endocrine emergency with a reported mortality as high as 85% (1, 2). Acute and rapidly progressive hemodynamic disturbances result from the actions of high quantities of catecholamines secreted by the tumor and lead to organ failure.
What drugs are used to treat pheochromocytoma?
An important aspect of BP control in pheochromocytoma is initial treatment with α-blockers and after achieving adequate α-blockade, the patient can be treated with β-blockers to achieve heart rate control. Phenoxybenzamine is a preferred α-blocker; however, prazosin, terazosin, doxazosin can also be used.
What medications should be avoided with pheochromocytoma?
Agents known to provoke a pheochromocytoma paroxysm (eg, beta-adrenergic blocker in absence of alpha-adrenergic blockade, glucagon, histamine, metoclopramide, high-dose corticosteroids) should be avoided. Our approach is largely consistent with the Endocrine Society’s 2014 Clinical Practice Guidelines [4].
Can you exercise with pheochromocytoma?
DON’T do strenuous exercise until your pheochromocytoma has been removed. DON’T expect that your high blood pressure will be completely normal after the operation. Some permanent changes may have already occurred in the kidneys and blood vessels.
Does pheochromocytoma cause constipation?
Objective. Pheochromocytomas (PHs) and sympathetic paragangliomas (PGs) are tumors that produce catecholamines, predisposing patients to cardiovascular disease and gastrointestinal effects such as constipation.
Can pheochromocytoma cause weight gain?
Compared to other adrenal tumor patients with cortisol- and aldosterone- producing tumors that tend to lose weight after operation, pheochromocytoma patients on average tend to gain some weight after successful surgery.
Can pheochromocytoma cause bloating?
Nausea. Vomiting. Belly (abdominal) pain or bloating.
