What is collagenase clostridium histolyticum used for?

What is collagenase clostridium histolyticum used for?

Collagenase clostridium histolyticum injection is used to treat Dupuytren’s contracture with a palpable cord. It is also used to treat Peyronie’s disease with a palpable plaque and curvature deformity in men.

How much does collagenase injection cost?

Total treatment cost for collagenase injection was US$1418.04 and for fasciectomy US$2102.56. The post-treatment median (IQR) total extension deficit was 10 (0–30) for the collagenase group and 10 (0–34) for the fasciectomy group.

Are collagenase injections painful?

Conclusions: Collagenase Clostridium histolyticum injection for treating Dupuytren contracture can be a painful process.

Do injections work for Peyronie’s disease?

Xiaflex injections are the only FDA-approved medical therapy for PD. The enzyme in the drug reduces the plaque, improving penile curvature. Xiaflex treatment cycles include two injection procedures. You’ll receive your second injection one to three days after your first injection appointment.

How many XIAFLEX injections do I need?

No more than 3 injections, each 4 weeks apart, should be given in the same area. If you are using this medication to treat Peyronie’s disease, the medication is injected into the plaque in the penis by your healthcare provider.

Are xiaflex injections covered by insurance?

The XIAFLEX Copay Assistance Program can cover up to $1200 of your out-of-pocket costs for each injection of XIAFLEX (collagenase clostridium histolyticum). How much you pay for XIAFLEX depends on your health benefits or insurance coverage.

What should I do after XIAFLEX injection?

You must return to your doctor’s office within 1 to 3 days after the procedure. Your doctor will check your hand, try to straighten the finger if needed, and apply a splint. Wear the splint every night at bedtime as long as directed by your doctor (for up to 4 months).

Does Xiaflex increase size?

Xiaflex with first generation PTT devices also had not impact on length. When patients used RestoreX along with the injection treatment, they experienced a nearly 2cm gain in length or about 17%.

Does XIAFLEX cause erectile dysfunction?

After treatment, one of the tubes inside the penis could break during an erection, called penile fracture. This typically requires surgery. Damage to the penis may not get better after penile fracture, even with surgery. This could lead to permanent inability to have an erection.

What are the side effects of XIAFLEX?

Pain, swelling, bruising, bleeding, redness, itching at or around the injection site may occur. Swollen, painful areas in the elbow and underarm (swollen lymph nodes) may also occur when this medication is injected in the hand. If any of these effects persist or worsen, tell your doctor promptly.

  • August 15, 2022