What is focal segmental glomerulosclerosis?

What is focal segmental glomerulosclerosis?

Focal segmental glomerulosclerosis is scar tissue in the filtering unit of the kidney. This structure is called the glomerulus. The glomeruli serve as filters that help the body get rid of harmful substances. Each kidney has thousands of glomeruli. “Focal” means that some of the glomeruli become scarred.

Which is a primary glomerular disease?

Primary glomerular disease means that the condition occurs on its own, without another known systemic disease such as lupus or diabetes. These diseases are also known as idiopathic (having no known cause), and cause Nephrotic Syndrome.

What is nephritic syndrome?

The nephritic syndrome is a clinical syndrome that presents as hematuria, elevated blood pressure, decreased urine output, and edema. The major underlying pathology is inflammation of the glomerulus that results in nephritic syndrome.

What are the symptoms of segmental glomerulosclerosis?

Signs and symptoms of FSGs include:

• Swelling in body parts like your legs, ankles and around your eyes (called edema)
• Weight gain due to extra fluid building in your body.
• Foamy urine caused by high protein levels in the urine (called proteinuria)
• High fat levels in the blood (high cholesterol)

What is the commonest cause of glomerular diseases?

Many diseases can cause glomerular disease. The leading cause is diabetes-related nephropathy.

Is nephrotic syndrome life expectancy?

Although nephrotic syndrome can be a serious condition most people respond well to treatment and can live essentially a normal life particular if the condition goes into remission. Depending on the cause patients may respond to treatment within a few days but may take several weeks or even months.

Is nephrotic syndrome fatal?

Prognosis. Congenital nephrotic syndrome may be successfully controlled in some cases with early and aggressive treatment, including early kidney transplantation, but many cases are fatal within the first year.

Can nephritis be reversed?

Although nephritis may not always be curable, proper treatment can keep the condition at bay and protect the kidneys. It is essential to follow the doctor’s instructions carefully to prevent and limit kidney damage. If kidney failure occurs, a person may require dialysis or a kidney transplant.

What are the signs and symptoms of nephritis?

What are the symptoms of acute nephritis?

• pain in the pelvis.
• pain or a burning sensation while urinating.
• a frequent need to urinate.
• cloudy urine.
• blood or pus in the urine.
• pain in the kidney area or abdomen.
• swelling of the body, commonly in the face, legs, and feet.
• vomiting.

What causes glomerulosclerosis?

Focal segmental glomerulosclerosis can be caused by a variety of conditions, such as diabetes, sickle cell disease, other kidney diseases and obesity. It can also be caused by an infection and drug toxicity. A rare form of FSGS is caused by inherited abnormal genes.

How do you repair damaged glomeruli?

Scarred glomeruli cannot be repaired. Treatment aims to prevent further damage and to avoid dialysis. The best treatment for glomerulosclerosis depends on what caused the scarring. The cause is determined by a kidney biopsy.

Can you reverse nephrotic syndrome?

There is no cure for nephrotic syndrome, but your doctor might tell you to take certain medicines to treat the symptoms and to keep the damage to your kidneys from getting worse. Medicine to control blood pressure and cholesterol can help prevent you from having a heart attack or a stroke.