What is the function of the granulosa cells of vascular follicles?
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What is the function of the granulosa cells of vascular follicles?
The granulosa cell (GC) is a critical somatic component of the ovary. It is essential for follicle development by supporting the developing oocyte, proliferating and producing sex steroids and disparate growth factors.
Where do the granulosa and theca cells originate from and what are their functions?
Solution : Granulosa cells and thecal cells surround the primary follicles to form secondary follicles in the ovaries. The innermost layer of granulosa cells that surround the oocyte is known as the corona radiata. A glycoprotein protective layer, known as the zona pellucida appears.
What is another name for granulosa cells?
follicular cell
A granulosa cell or follicular cell is a somatic cell of the sex cord that is closely associated with the developing female gamete (called an oocyte or egg) in the ovary of mammals.
What is a theca Folliculi?
Medical Definition of theca folliculi : the outer covering of a graafian follicle that is made up of the theca externa and theca interna.
What hormone do granulosa cells produce?
The granulosa cells respond to follicle stimulating hormone (FSH) and produce estrogen.
What is the function of inhibin in the ovary?
inhibin, hormone secreted by the granulosa cells in the ovaries of women that acts primarily to inhibit the secretion of follicle-stimulating hormone by the anterior pituitary gland.
How granulosa cells are formed?
They are derived from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the OOCYTE in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the OVUM in the Graafian follicle.
What is the function of the theca externa?
Cells of the theca externa contribute structural support to the growing follicle and maintain cyclic adenosine monophosphate (cAMP)-dependent smooth muscle-like function, which is necessary for successful ovulation of the developed oocyte. Cells of the theca interna are necessary for production of ovarian androgens.
How do granulosa cells form?
They develop from the coelomic epithelial cells of the gonadal ridge. Granulosa cells form a single layer around the mammalian oocyte in the primordial ovarian follicle and advance to form a multilayered cumulus oophorus surrounding the ovum in the Graafian follicle.
What is inhibin function?
Inhibin is a protein secreted by the Sertoli cells in men and by the granulosa cells in women. It inhibits the synthesis and release of the follicle-stimulating hormone in the pituitary gland and reduces the hypothalamic LH – releasing hormone content.
