What is the structure of Trypanosoma cruzi?
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What is the structure of Trypanosoma cruzi?
As previously described T. cruzi has a single tubular mitochondrion which shares with the similar organelle from mammalian cells some features as the presence of DNA, cristae and a number of enzymes detected in its interior membrane.
Where can epimastigote stage Trypanosoma cruzi be found?
The epimastigote stage is not seen in humans but can be found in the midgut of triatomines that have ingested trypomastigotes from an infected host. Figure A: Trypanosoma cruzi epimastigote from culture.
Does Trypanosoma cruzi have nuclei and/or flagella?
cruzi takes place without nuclear division and progresses through an intermediate stage (2K1N) with duplicate flagella, basal body and kinetoplast, but only a single nucleus.
What is the classification of Trypanosoma cruzi?
KinetoplastidaTrypanosoma cruzi / Class
What are the developmental stages of Trypanosoma?
The life cycle of Trypanosoma cruzi involves two intermediate hosts: the invertebrate vector (triatomine insects) and the vertebrate host (humans) and has three developmental stages namely, trypomastigotes, amastigotes and epimastigotes [8].
What is the difference between amastigote and trypomastigote?
Amastigogenesis occurs first when metacyclic trypomastigotes from triatomine urine differentiate into amastigotes inside mammalian host cells and a secondary process when tissue-derived trypomastigotes invade new cells and differentiate newly to amastigotes.
What are the characteristics of Trypanosoma cruzi?
Trypanosoma cruzi, the etiological agent of Chagas disease, or American trypanosomiasis, is a flagellate of the Kinetoplastida order, family Trypanosomatidae, characterized by the presence of one flagellum and a single mitochondrion in which the kinetoplast, a specialized DNA-containing organelle, is situated.
Does Trypanosoma cruzi have nuclei?
In epimastigotes and amastigotes, which are the replicating stages of Trypanosoma cruzi, the protozoan parasite that causes Chagas’ disease, the nucleus is spherical and contains a large nucleolus and small amounts of heterochromatin.
What is the characteristics of Trypanosoma?
Trypanosome cells are small and heterotrophic; they share common characteristics with other members of the phylum Euglenozoa, particularly the stiffening paraxial rod in the flagellum, and characteristics common to the order Kinetoplastida, specifically a large clump of DNA located at one end of the unusually long …
What are Trypanosoma and in which group are they classified?
Trypanosoma is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa. Trypanosoma is part of the phylum Sarcomastigophora. The name is derived from the Greek trypano- (borer) and soma (body) because of their corkscrew-like motion.
What is the molecular classification of Trypanosoma?
protozoal parasite trypanosomes are grouped in the order “kinetoplastida” because of the presence of a kinetoplast (discussed later). Based on the mode of transmission by their insect vector, the genus Trypanosoma is divided in two main groups: ster- coraria and salivaria [11,12] (Figure 2).
What is the infective stage of Trypanosoma cruzi?
The trypomastigote is the infective flagellated form of the parasite found in the blood of the mammalian hosts (blood trypomastigote) and in the hindgut of vectors (metacyclic trypomastigote). Image courtesy of Peter Darben, MD. Chagas disease (American trypanosomiasis).
What is Amastigote and Promastigote?
Leishmania parasites are dimorphic organisms that live and replicate in the gut of sandflies as flagellated forms (promastigote) or as aflagellated forms (amastigotes) in mammalian cells. In the mammalian host these parasites preferentially infect phagocytic cells, primarily macrophages and dendritic cells.
Does the Amastigote have a flagellum?
Morphology of L. amazonensis during differentiation of amastigote to promastigote forms. (A) At 0 h, amastigotes have a short flagellum inside the flagellar pocket (arrow).
What is the function of nucleus in Trypanosoma?
The nucleus compartmentalizes the genetic material surrounded by a double membrane called nuclear envelope.
Is Trypanosoma cruzi motile?
Trypanosoma cruzi trypomastigotes and epimastigotes are propelled by a single flagellum, via mechanochemical oscillations that generate motile forces.
What type of protozoa is Trypanosoma?
Trypanosoma is a genus of kinetoplastids (class Trypanosomatidae), a monophyletic group of unicellular parasitic flagellate protozoa.
