What system does Pompe affect?

What system does Pompe affect?

Pompe disease happens when your body can’t make a protein that breaks down a complex sugar, called glycogen, for energy. Too much sugar builds up and damages your muscles and organs. Pompe disease causes muscle weakness and trouble breathing. It mostly affects the liver, heart, and muscles.

What organelle is affected by Pompe disease?

The defect results in a build-up of glycogen in the lysosome, a saclike storage organelle in the cell that acts as a waste-disposal system, leading to muscle weakness, organ damage including the brain, and possible death.

Can Pompe disease be cured?

Medical Care. Unfortunately, no cure exists. However, Pompe disease has benefited from the introduction of enzyme replacement therapy (ERT), which, although expensive, is a major therapeutic advance.

Why does Pompe’s disease cause muscle weakness?

Pompe disease is an inherited disorder caused by the buildup of a complex sugar called glycogen in the body’s cells. The accumulation of glycogen in certain organs and tissues, especially muscles, impairs their ability to function normally.

What are the symptoms of low enzymes?

Symptoms of Digestive Enzyme Insufficiency

• Belly pain or cramps.
• Bloating.
• Diarrhea.
• Gas.
• Oily stools (bowel movements)
• Unexplained weight loss.

Which diseases can be treated with enzyme therapy?

ERT for Pompe disease is the only effective treatment available today….Pompe Disease

• Poor muscle development.
• Trouble eating, breathing, and/or hearing.
• Respiratory problems.
• Enlarged liver and/or heart.
• Problems with motor function.

What happens when you take too many digestive enzymes?

What happens if I take too many pancreatic enzymes? Any pancreatic enzymes that your body doesn’t need will pass through you. If you take one or two more capsules than you need, this won’t be a problem. If you take lots more than you need it may cause some itching around your anus (bottom).

How can I increase my digestive enzymes naturally?

Foods that contain natural digestive enzymes include pineapples, papayas, mangoes, honey, bananas, avocados, kefir, sauerkraut, kimchi, miso, kiwifruit and ginger. Adding any of these foods to your diet may help promote digestion and better gut health.

How do I know if my digestive enzymes are working?

Many of the uncomfortable reactions such as an upset stomach, allergy-like symptoms or irritability are actually signs that the enzymes are working. The body is cleaning itself out and the healing process is starting.