Which disorder have overlapping features with Marfan syndrome?
Table of Contents
Which disorder have overlapping features with Marfan syndrome?
Loeys-Dietz syndrome (LDS) is a rare disorder characterized by a variety of symptoms that overlap with Marfan syndrome.
Which of these conditions presents similar to Marfan syndrome?
Ectopia lentis syndrome is an inherited connective tissue disorder that shares some of the features of Marfan syndrome – particularly lens dislocation of the eye, which can cause serious vision problems.
What serious problems does Marfan cause?
Marfan syndrome can damage the blood vessels, heart, eyes, skin, lungs, and the bones of the hips, spine, feet, and rib cage. Some complications of Marfan syndrome can be treated or prevented, including heart disease, bone deformities such as a curved spine, eye conditions, crooked teeth, and collapsed lungs.
What are common names for Marfan syndrome?
| Marfan syndrome | |
|---|---|
| Other names | Marfan’s syndrome |
| Ectopia lentis in Marfan syndrome: Zonular fibers are seen. | |
| Specialty | Medical genetics |
| Symptoms | Tall, thin build; long arms, legs and fingers; flexible fingers and toes |
Is Marfan syndrome related to Ehlers-Danlos Syndrome?
Ehlers-Danlos syndromes (EDS) and Marfan syndrome (MFS) are multisystemic disorders that primarily affect the soft connective tissues. Both disorders have benefited from recent advances in clinical and molecular characterization, allowing improvements in clinical diagnosis and management.
Is Marfan syndrome similar to other cardiovascular disease?
Virtually all adults with Marfan’s syndrome have an abnormal cardiovascular system. In early childhood, however, the features may be mild and easily missed. The most common cardiovascular abnormalities are dilatation of the aorta and mitral regurgitation (table 2).
Which substance fails to form normally in individuals with Marfan syndrome?
A mutation in the FBN1 gene can reduce the amount of functional fibrillin-1 that is available to form microfibrils, which leads to decreased microfibril formation.
Are there different degrees of Marfan syndrome?
The symptoms of Marfan syndrome differ from one person to the next, depending on which body part is affected and to what degree. Some people may not even realise they have the condition, because their features are either mild or not obvious.
What is Loeys-Dietz syndrome?
Loeys-Dietz syndrome is a connective tissue disorder that was first described in 2005. Most individuals with this disorder have craniofacial features that include hypertelorism (widely spaced eyes) and a bifid or broad uvula.
What’s the opposite of Marfan syndrome?
Loeys-Dietz Syndrome | Johns Hopkins Medicine.
What is Gaucher’s disease?
Gaucher (go-SHAY) disease is the result of a buildup of certain fatty substances in certain organs, particularly your spleen and liver. This causes these organs to enlarge and can affect their function. The fatty substances also can build up in bone tissue, weakening the bone and increasing the risk of fractures.
Does Marfan syndrome affect mental health?
In addition, some MFS patients also have psychiatric symptoms such as depression and anxiety. As with many genetic disorders, patients with MFS also have concerns with various aspects of life, such as family planning and finances related to health care.
