Why are we still using hydrochlorothiazide?
Table of Contents
Why are we still using hydrochlorothiazide?
It is well accepted that a low to medium dose of a diuretic such as HCTZ (12.5–25 mg/d) is effective in lowering blood pressure (BP) with considerably fewer metabolic side effects than were seen in the days when HCTZ was prescribed in doses of 50 mg/d or even 100 mg/d.
Which is better HCTZ or chlorthalidone?
Chlorthalidone is better at lowering the risk of a cardiovascular event, such as a heart attack. Even after chlorthalidone and HCTZ achieve the same blood pressure, chlorthalidone lowers the risk of a cardiovascular event by about 20% more than HCTZ.
Do thiazides have mortality benefit?
No trial has documented a mortality benefit from hydrochlorothiazide. This topic will review the antihypertensive mechanisms of thiazide and thiazide-like therapy, the common side effects associated with high doses of these diuretics, and the benefits of low-dose therapy.
Can I take vitamin d3 with hydrochlorothiazide?
hydroCHLOROthiazide cholecalciferol Using hydroCHLOROthiazide together with cholecalciferol can cause your blood calcium levels to become too high. Contact your doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures.
What is the safest diuretic for elderly?
Conclusions. Low dose treatment with thiazide or thiazide like diuretics in adults aged 65 and older is in general appropriate.
Is HCTZ a good blood pressure medicine?
Hydrochlorothiazide is used alone or together with other medicines to treat high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly.
How much weight can you lose on HCTZ?
The effective dose of hydrochlorothiazide in 52% of these responders was 50 mg/day, and this was associated with weight loss averaging 1.58 kg. An additional 29% achieved goal BP with a similar degree of weight loss, but they required double the dose, or 100 mg/day.
What is the safest hypertension medication?
Methyldopa, which works to lower blood pressure through the central nervous system, has the lowest risk of harming the mother and developing fetus. Other possible safe options include labetalol, beta-blockers, and diuretics.
