What does HCV genotype 1a mean?

What does HCV genotype 1a mean?

Hepatitis C virus (HCV) genotype 1 is the most prevalent worldwide. Subtype 1a, compared with 1b, shows lower response rates and higher propensity to select for drug resistance to NS3 and selected NS5A and nonnucleoside NS5B inhibitors.

What does HCV cirrhosis mean?

Rizza, M.D. End-stage hepatitis C means the liver has been severely damaged by the hepatitis C virus. The hepatitis C virus slowly damages the liver over many years, often progressing from inflammation to permanent, irreversible scarring (cirrhosis).

Is HCV a death sentence?

While hepatitis C may have been a death sentence a generation ago, a potential cure is already giving some patients a new lease on life.

How long does it take for hep C to cause cirrhosis?

From those who develop a chronic or long term infection (between 70-80% of those infected with hepatitis C) around 20-30% will develop cirrhosis within 20 years. For some it may be quicker while for others it may take up to sixty years, meaning they will probably die of unrelated causes first.

What is the normal range for HCV?

Normal range for this assay is “Not Detected”. The quantitative range of this assay is 10 – 100,000,000 IU/mL (1.0 – 8.0 log IU/mL).

Can cirrhosis from hep C be reversed?

Recent studies have confirmed that if you have fibrosis – or even cirrhosis – and are treated and cured of hep C, the development of fibrosis will stop, and fibrosis will reverse in the majority of patients. Liver damage reversal is possible even when cirrhosis has developed.

Does cirrhosis improve after hep C treatment?

Hepatitis C virus (HCV)-related liver fibrosis improves significantly in the majority of people with pre-treatment advanced fibrosis or cirrhosis after treatment resulting in a sustained virological response, Swedish investigators report in the Journal of Viral Hepatitis.

How do you know what stage of cirrhosis you have?

Biopsy: A sample of liver tissue (biopsy) is removed from your liver and examined under the microscope. A liver biopsy can confirm a diagnosis of cirrhosis, determine other causes or extent of liver damage or enlargement or diagnosis liver cancer.

What is a high level for hep C?

High viral load: This is when your count is more than 800,000 IU/mL. If your viral count is high at the start, it can be hard or impossible for your treatment to completely get rid of the virus. Some researchers consider high levels anything above 400,000 IU/mL.

Does Hep C shorten your life?

Complications from untreated hepatitis C, including cirrhosis (liver scarring) and liver cancer, can be fatal, though HCV itself is rarely fatal.

What is Stage 1 cirrhosis of the liver?

During stage 1, cirrhosis is so mild it’s often difficult for physicians to detect. The most common symptom is fatigue. The cirrhosis is still reversible during this stage, but not enough liver tissue has been damaged to produce obvious symptoms of disease.

How do you know what stage your cirrhosis is?

Can hep C cirrhosis be reversed?

Liver damage reversal is possible even when cirrhosis has developed. A recent review of multiple studies found that 53 percent of patients who were cured of hep C had regression of cirrhosis.