What does spindle cell neoplasm mean?

What does spindle cell neoplasm mean?

Spindle cell neoplasms are defined as neoplasms that consist of spindle-shaped cells in the histopathology. Spindle cell neoplasms can affect the oral cavity. In the oral cavity, the origin of the spindle cell neoplasms may be traced to epithelial, mesenchymal and odontogenic components.

Is spindle cell neoplasm cancerous?

Spindle cell sarcoma is a rare malignant (cancerous) tumour which can develop in the bone or soft tissue. It can arise in any part of the body but is most common in the limbs (arms and legs).

What is the survival rate for spindle cell carcinoma?

The median overall survival time was 8.89 months. The 1-year overall survival rate was 36.7% and the 3-year overall survival rate was 27.5%. In the early stage group, the 1-year and 3-year survival rates were both 100%.

What causes spindle cell neoplasm?

Siegel says the cause of spindle cell sarcoma is unknown. There is a genetic predisposition; however, it is not commonly thought to be hereditary. Some rare, inherited genetic conditions are considered risk factors for soft-tissue sarcoma.

Can spindle cell sarcoma be cured?

The best chance to cure a soft tissue sarcoma is to remove it with surgery, so surgery is part of the treatment for all soft tissue sarcomas whenever possible. It’s important that your surgeon and other doctors are experienced in the treatment of sarcomas.

How serious is spindle cell sarcoma?

Spindle cell sarcoma is a soft-tissue tumour which can start in the bone. Spindle cell sarcomas of the bone are often found in the arms, legs and pelvis. They most commonly arise in patients over the age of 40 and are extremely rare, making up just 2-5% of all primary bone cancer cases.

What is a spindle-cell neoplasm?

A spindle-cell neoplasm is a general term used to describe an abnormal growth (a neoplasm) made up of spindle cells (cells that are longer than they are wide). Spindle-cell neoplasm is considered a general term because it includes many different types of benign (non-cancerous) and malignant (cancerous) growths.

What is atypical spindle cell lipomatous tumor?

Atypical spindle cell lipomatous tumor is a distinctive adipocytic neoplasm that usually affects middle-aged adults and most commonly arises in subcutaneous tissue of the extremities or trunk.

What is the pathophysiology of spindle cell carcinoma (SPCC)?

The most common spindle cell lesion presenting along the UADT mucosa is spindle cell carcinoma (SpCC), which has many unique and challenging clinical and pathologic features. The spindle cell or sarcomatoid component of this tumor can mimic numerous other reactive, benign, and malignant lesions (Table 1).

Where do spindle cell lesions occur in the body?

Spindle cell lesions can occur in head and neck skin, in the soft tissues of the scalp, orbit, and neck, and along the upper aerodigestive tract (UADT) mucosa. The most common spindle cell lesion presenting along the UADT mucosa is spindle cell carcinoma (SpCC), which has many unique and challenging clinical and pathologic features.