What hormones come from the zona fasciculata and the zona reticularis?
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What hormones come from the zona fasciculata and the zona reticularis?
Situated between the glomerulosa and reticularis, the cells of the zona fasciculata synthesize and secrete glucocorticoids, such as 11-deoxycorticosterone, corticosterone, and cortisol in humans. The major hormone that stimulates cortisol secretion in humans is the ACTH that is released from the anterior pituitary.
What is the function of the zona glomerulosa zona fasciculata and the zona reticularis?
Zona fasciculata is the layer situated between the glomerulosa and reticularis. This layer is responsible for producing glucocorticoids, such as cortisol. Zona reticularis is the inner most cortical layer; the zona reticularis produces androgens, mainly DHEA.
What adrenal gland hormone is secreted by zona reticularis?
DHEA
DHEA and Androgenic Steroids These hormones produced by the zona reticularis are weak male hormones. They are precursor hormones that are converted in the ovaries into female hormones (estrogens) and in the testes into male hormones (androgens).
What are the effects of zona fasciculata?
The cells of the Zona Fasciculata secrete the glucocorticoids Cortisol and Corticosterone. These hormones regulate carbohydrate metabolism, particularly when an individual is in a time of stress (as part of the “fight-or-flight” response).
What is the function of zona reticularis?
The zona reticularis is the site of biosynthesis of androgen precursors such as dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. These androgens are released into the bloodstream and transported to gonads where they are converted into testosterone or oestrogen.
What is produced in the inner zone zona reticularis of the adrenal cortex?
The zona reticularis is the innermost zone of the adrenal cortex. The presence of 17α-hydroxylase and 17,20-lyase results in the production of dehydroepiandrosterone (DHEA), sulfated DHEA (DHEA-S), and androstenedione to this region, although some androgen synthesis also occurs in the zona fasciculata.
What is the function of zona glomerulosa?
The primary function of the zona glomerulosa is the synthesis of mineralocorticoid hormones, which play an important role in the maintenance of electrolyte and water balance in the body. Mineralocorticoids are steroid hormones, and so are synthesised from cholesterol.
Which hormone is released from zona glomerulosa?
Aldosterone
Aldosterone. Aldosterone secretion by the zona glomerulosa cells of the adrenal gland is normally regulated by Ang II and potassium, which is mediated by an increase in intracellular calcium. ACTH becomes a very important stimulus of aldosterone secretion under conditions of volume depletion.
What does zona glomerulosa secretes?
aldosterone
The cells of zona glomerulosa, a few layers of cells just beneath the adrenal capsule, synthesize and secrete aldosterone, whereas those of zonae fasciculata and reticularis secrete glucocorticoids and androgens, respectively.
What does zona reticularis secrete in females?
Cells in the zona reticularis produce precursor androgens including dehydroepiandrosterone (DHEA) and androstenedione from cholesterol. DHEA is further converted to DHEA-sulfate via a sulfotransferase, SULT2A1….
| Zona reticularis | |
|---|---|
| FMA | 69236 |
| Anatomical terminology |
What does the zona glomerulosa produce?
The zona glomerulosa produces mineralocorticoids, the zona fasciculata produces glucocorticoids, and the zona reticularis produces androgen precursors (mostly DHEA with some androstenedione).
What is the arrangement of the cells of the zona reticularis?
The zona reticularis is the innermost layer of the adrenal cortex, lying just above the adrenal medulla. It comprises of cylindrical masses of epithelia arranged in an irregular, net-like pattern.
What stimulates the zona fasciculata?
ACTH is the main stimulus of the zona fasciculata and zona reticularis, stimulating glucocorticoid secretion, while angiotensin II and potassium are the main stimuli of aldosterone secretion by the zona glomerulosa.
What is the arrangement of the cells of the zona glomerulosa?
The cells of the zona glomerulosa are arranged in loops and arcades 1-2 cells thick. The nuclei are round and the cytoplasm may contain a few lipid droplets, which will appear as lipid vacuoles.
