What is emulgel formulation?

What is emulgel formulation?

Emulgel are prepared by incorporating gel and emulsion. The emulsion and gel are prepared separately and mixed together. For preparing emulsion, aqueous phase and oil phase are taken separately and mixed together. Then the gel is prepared by using gelling agent.

What is the difference between gel and emulgel?

When gel and emulsion used in the combined form, they are referred as Emulgel. Emulgel is the promising drug delivery system for the delivery of hydrophobic drugs. Emulgel is an emulsion which is gelled by mixing it with gelling agents. Many advantages of gels have the major limitation of delivery of hydrophobic drugs.

What is Emul gel?

Emulgel [1-4] As the name suggest, they are the combination of gel and emulsion. Both oil-in-water and water-in-oil type of emulsion used as a vehicle to deliver various drugs to the skin. They also have a high ability to penetrate the skin.

How do you make diclofenac gel?

Formulation batch F7 (2% Diclofenac, 10%PG, 0.15%Methylparaben, 0.05%Propyl Paraben,1.5Êrbopol 940, 67.44%ethanol,16.86%water) had shown higher amount of percent cumulative release as compared to marketed gel(Intas pharmaceutical). Spreadiability of formulation F7 was good to cover the painful area.

Is Voltaren emulgel the same as Voltaren Gel?

Voltaren gel There are two formulations of Voltaren that can be applied to the skin, each of which offers its own range of benefits. Voltaren Emulgel contains 1.16% of diclofenac diethylammonium in a gel form. It is suitable for 3-4 applications a day for short-term pain relief, or for longer periods up to 2 weeks.

What are hydrophobic drugs?

The term “hydrophobic drugs” roughly describes a heterogeneous group of molecules that exhibit poor solubility in water but that are typically, but certainly not always, soluble in various organic solvents.

What is gelling agent made from?

Gelatin is one of the most commonly used gelling agents. It is derived from denatured collagen, and a useful review of its properties in general can be found in Djabourov (1988).

What are the ingredients in diclofenac sodium topical gel?

It has the following structural formula: Diclofenac sodium topical gel, 1% also contains carbomer homopolymer Type C, cocoyl caprylocaprate, fragrance, isopropyl alcohol, mineral oil, polyoxyl 20 cetostearyl ether, propylene glycol, purified water, and strong ammonia solution.

What is diclofenac sodium gel 1% used for?

Diclofenac is used to treat pain and other symptoms of arthritis of the joints (eg, osteoarthritis), such as inflammation, swelling, stiffness, and joint pain. However, this medicine does not cure osteoarthritis and will help you only as long as you continue to use it.

What are the ingredients in Voltaren emulgel?

Voltaren® Emulgel – Joint Pain Regular Strength Nonmedicinal ingredients: carbomer, cocoyl caprylocaprate, diethylamine, isopropyl alcohol, liquid paraffin, macrogol cetostearyl ether, perfume, propylene glycol, and purified water.

What is the generic Name for Voltaren Gel?

Generic Name: diclofenac sodium This medication is used to relieve joint pain from arthritis. Diclofenac belongs to a class of drugs known as nonsteroidal anti-inflammatory drugs (NSAIDs).

What is log P of a drug?

The Log P value of the compound indicates the permeability of the drugs to reach the target tissue in the body.

Is Carbopol gelling agent?

Carbopol®* is a water soluble polymer, used as an emulsifying, stabilising, suspending, thickening in many industries and is also used as gelling agent in hand sanitizer gels and other products.

What is the active ingredient in Voltaren Gel?

1 g Voltaren Emulgel contains 11.6 mg of the active ingredient, diclofenac diethylammonium. You should not use Voltaren Emulgel if: you are allergic to diclofenac, propylene glycol, isopropyl alcohol or any of the other ingredients.

What is the brand name for diclofenac sodium topical gel?

Diclofenac topical gel is available as a brand-name drug and a generic drug. Brand names: Solaraze, Voltaren.

Is Voltaren emulgel the same as Voltaren gel?

What is the generic name of Voltaren?

Generic Name: diclofenac sodium Diclofenac is used to relieve pain, swelling (inflammation), and joint stiffness caused by arthritis. Reducing these symptoms helps you do more of your normal daily activities. This medication is known as a nonsteroidal anti-inflammatory drug (NSAID).