What is the survival rate for HER2-positive breast cancer?

What is the survival rate for HER2-positive breast cancer?

The survival rate at four years among women with HR+/HER2− is estimated to be 92.5%, followed by HR+/HER2+ at 90.3%, HR−/HER2+ at 82.7%, and HR−/HER2− at 77.0% [1]. The HER2 (human epidermal growth factor receptor 2) oncogene is positive in about 20% of primary invasive breast cancers [2].

Can you be cured from HER2-positive breast cancer?

HER2-positive breast cancer is highly curable because of the availability of these HER2-targeted therapies, so we treat patients fairly aggressively upfront to reduce the risk of them experiencing a stage IV recurrence.

Is it better to have HER2-positive breast cancer?

Breast cancer identified as HER2-positive tends to grow faster, spread (metastatic breast cancer) and come back (recur). While HER2-positive cancer may be aggressive, it also responds better to breast cancer treatment that targets HER2 protein.

Can Stage 3 HER2-positive breast cancer be cured?

With recent advances in medicine, it is considered that HER2-positive breast cancer is curable. Targeted therapy is used to cure HER2-positive breast cancer. However, surgery, radiation therapy, chemotherapy and hormonal therapy may also be combined with targeted therapy depending on cancer aggressiveness.

Where does HER2-positive breast cancer come back?

Lymph nodes near the breast tend to be the next place cancer cells go. From there, cancer cells can travel to other parts of the body farther from the breast. About one in every five breast cancers are HER2-positive. This means they have extra copies of a gene that makes the HER2 protein.

What is a good HER2 score?

Testing for HER2 status The IHC gives a score of 0 to 3+ that measures the amount of HER2 proteins on the surface of cells in a breast cancer tissue sample. If the score is 0 to 1+, it’s considered HER2-negative. If the score is 2+, it’s considered borderline. A score of 3+ is considered HER2-positive.

What are the chances of HER2-positive cancer returning?

The researchers found: 10% to 23% of women diagnosed with small, HER2-positive cancer had a recurrence within 5 years of diagnosis compared to about 5% of women diagnosed with HER2-negative cancer.

Does HER2-positive run in families?

HER2-positive breast cancer is not hereditary, but some other types of gene mutations related to breast cancer are inherited. Genetic testing can tell you if you have any of the mutations currently known to increase risk for breast cancer or other cancers.

Are you born with HER2-positive?

HER2-positive breast cancer is not inherited. Instead, it’s considered a somatic genetic mutation. This type of mutation occurs after conception. Having a close relative with HER2-positive breast cancer does not increase your risk for breast cancer or HER2-positive breast cancer.