Which vaccines are cell based?
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Which vaccines are cell based?
Cell culture technology has been used to produce other U.S.-licensed vaccines, including vaccines for rotavirus, polio, smallpox, hepatitis, rubella and chickenpox. Cell-based flu vaccines have been approved for use in many European countries.
What is fetal tissue?
Human fetal tissue is defined as tissue or cells obtained from a dead human embryo or fetus after a spontaneous or induced abortion or stillbirth. This definition does not include established human fetal cell lines.
How are fetal stem cells obtained?
Embryonic stem cells are obtained from early-stage embryos — a group of cells that forms when eggs are fertilized with sperm at an in vitro fertilization clinic.
Is fetal tissue used in medical research?
Fetal tissue has been used in many types of medical research, including the development of vaccines for polio, measles and other diseases, and in therapies to treat Parkinson’s diseases, diabetes and rheumatoid arthritis, and to prevent the transmission of HIV.
What is tissue culture vaccine?
Abstract. Cell culture-based viral vaccines are used globally to immunize humans against infections. The cell culture is continuous process of developing substrates for the safe production of viral vaccines.
How is fetal tissue used in research?
Fetal tissue research involves cells from dead fetuses that are harvested for the purpose of establishing cell lines or for use as transplantation material and other purposes. There are two sources of such fetal tissue—elective (or induced) abortions and spontaneous (or natural) abortions.
What is placental tissue?
Placental tissues including the placental disc, umbilical cord, amniotic fluid and amniotic sac are highly specialized tissues responsible for transporting nutrients and coordinating developmental cues during pregnancy and fetal development.
Are stem cells the same as fetal cells?
The developing organs and tissues in a fetus contain a relatively large supply of stem cells because they are needed for growth and maturation. The difference between embryonic stem cells and fetal stem cells is the fetal stem cells have matured part of the way to mature cells.
When did fetal tissue research start?
1930s
Fetal tissue research dates back to the 1930s, and has led to major advances in human health, including the virtual elimination of such childhood scourges as polio, measles and rubella in the United States.
Does collagen come from babies?
Some of the dark places that collagen comes from include human foreskins and stem cells. On a collagen product, you won’t see these words in particular. If a product contains human foreskins, you will see neonatal fibroblasts on the label. Notably, the foreskins used come from babies.
Which animal kidney is used for preparing polio vaccine?
Polio vaccines used in the late 1950s and early 1960s were contaminated with a virus called simian virus 40 (SV40) present in monkey kidney cells used to grow the vaccine.
What is WI-38 in vaccines?
The WI-38 cell line is used as a culture to grow live viruses that are used in vaccines. “Merck, as well as other vaccine manufacturers, uses two well-established human cell lines to grow the virus for selected vaccines,” Merck said in a statement to ABC News.
Is the placenta fetal tissue?
The placenta is a fetal tissue embedded in the wall of the uterus and perfused with maternal blood from the uterine spiral arteries.