Is Provigil safe during pregnancy?

Is Provigil safe during pregnancy?

Modafinil (Provigil): increased risk of congenital malformations if used during pregnancy. Modafinil potentially increases the risk of congenital malformations when used in pregnancy.

Is Provigil a controlled substance?

Is Provigil a controlled substance? Yes, Provigil is a controlled substance. It’s classified as a schedule IV prescription drug. This means it has an accepted medical use but may also cause physical or psychological dependence and may be abused.

How is modafinil metabolized?

Modafinil is primarily eliminated via metabolism, mainly in the liver, with subsequent excretion in the urine. Less than 10% of the dose is excreted as unchanged drug. Metabolism is largely via amide hydrolysis, with lesser contributions from cytochrome P450 (CYP)-mediated oxidative pathways.

Does modafinil cause miscarriage?

Intrauterine growth restriction and spontaneous abortion have been reported with modafinil (a mixture of R-and S-modafinil) and armodafinil (the R-enantiomer of modafinil).

Does modafinil affect fertility?

There are no clinical trials to investigate whether Modafinil can affect fertility in humans, but animal studies show that Modafinil does not lead to fertility problems.

Which is stronger Provigil or Nuvigil?

Provigil vs Nuvigil It allows people to start at lower doses and go up to higher doses over time if needed. A study by M. Darwish and colleagues published in 2009 in Clinical Drug Investigation found that Nuvigil blood concentrations were higher than Provigil late in the day.

Can you drink on modafinil?

As a rule, you must not mix Modafinil with alcohol. Any healthy people who take Modafinil for its cognitive-enhancing effects have stated that blackouts can be caused by combining Modafinil with alcohol. Others, after consuming more drinks than usual, report increased alcohol tolerance and trouble feeling intoxicated.

What can you not mix with modafinil?

Patients may take modafinil with or without food. Notes for Consumers: Limit excessive caffeine intake (examples: coffee, teas, colas, chocolate and some herbal supplements) while taking Modafinil. Also avoid medicines containing additional Caffeine whenever possible.

Does modafinil cause weight gain?

Increased Level of Dopamine Also, Modafinil, when used with other drugs, can lead to an increase in weight loss.

Can you take Armodafinil while pregnant?

During pregnancy, the FDA classifies armodafinil as a category C drug. This means that it may be unsafe during pregnancy, but there’s not enough clear evidence to definitively say it is safe. There is an additional issue to consider with regard to armodafinil and pregnancy.

How long is modafinil in your system?

The normal half-life of modafinil in humans is between 12 to 15 hours [4].

Is Provigil hard on the liver?

CNS stimulants (applies to Provigil) liver disease Therapy with CNS stimulants should be administered cautiously in patients with moderate to severe liver disease, and the dosage should be adjusted accordingly. Additionally, postmarketing reports have shown that atomoxetine can cause severe liver injury.

Can you drink alcohol while taking Nuvigil?

Notes for Consumers: Avoid alcohol-containing beverages while taking Armodafinil. Alcohol may cause drowsiness and other side effects which may decrease the effectiveness of Armodafinil. Notes for Professionals: Advise patients to avoid alcohol-containing beverages while taking armodafinil.

What happens if you drink on Provigil?

Some healthy individuals taking Modafinil for its cognitive-enhancing effects have reported that mixing Modafinil with alcohol may cause blackouts. Others experience a heightened alcohol tolerance and difficulty feeling drunk despite having more drinks than normal.

Can you drink alcohol after taking modafinil?

Does modafinil cause liver damage?

Both modafinil and armodafinil are associated with a low rate of serum aminotransferase elevations during therapy, but they have not been implicated in cases of clinically apparent acute liver injury.