What are some rare blood disorders?

What are some rare blood disorders?

MPNs include:

• Polycythemia vera (PCV)
• Myelofibrosis.
• Essential thrombocythemia.
• Eosinophilia.
• Mastocytosis.
• Histiocytosis. Langerhans cell histiocytosis (LCH) Erdheim-Chester disease (ECD) Rosai-Dorfman disease (RDD)
• Paroxysmal nocturnal hemoglobinuria (PNH)

What are the symptoms of Churg-Strauss syndrome?

Symptoms

• Loss of appetite and weight loss.
• Joint and muscle pain.
• Abdominal pain and gastrointestinal bleeding.
• Weakness, fatigue or a general feeling of being unwell.
• Rash or skin sores.
• Pain, numbness, and tingling in your hands and feet.

What is the life expectancy of someone with Churg-Strauss syndrome?

Overall, without treatment, the 5-year survival rate in EGPA is about 25%. With treatment, the 1-year survival rate is 90% and the 5-year survival rate is 62%.

What are fatal blood disorders?

Blood cancers (leukemia, lymphoma, multiple myeloma) and sickle cell anemia can be fatal.

What is Takayasu’s arteritis disease?

Takayasu’s arteritis, also called TAK, is a rare form of vasculitis disease involving inflammation in the walls of the largest arteries in the body: the aorta and its main branches. The disease results from an attack by the body’s own immune system, causing inflammation in the walls of arteries.

What is eosinophilic disorder?

Eosinophilic disorders are characterized by increased levels of eosinophils in one or more places in the digestive tract. Eosinophils are white blood cells that play a role in fighting parasites and allergic reactions. The esophagus, stomach, small intestine and large intestine (colon) may be affected.

What is a distinctive finding in patients who have Churg-Strauss syndrome?

Nonspecific findings associated with Churg-Strauss syndrome typically include flu-like symptoms, such as fever, a general feeling of weakness and fatigue (malaise), loss of appetite (anorexia), weight loss, and muscle pain (myalgia).

What is PNH disease?

Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood. The disease is characterized by destruction of red blood cells, blood clots, and impaired bone marrow function. PNH is closely related to aplastic anemia.

What is Periarteritis Nodosa?

Polyarteritis nodosa is a rare multi-system disorder characterized by widespread inflammation, weakening, and damage to small and medium-sized arteries. Blood vessels in any organ or organ system may be affected, including those supplying the kidneys, heart, intestine, nervous system, and/or skeletal muscles.

Can giant cell arteritis cause shortness of breath?

pain or pressure that radiates to your jaw, shoulders, or left arm. nausea. shortness of breath.

What is Eosinopenia when does it occur?

Eosinopenia is a form of agranulocytosis where the number of eosinophil granulocytes is lower than expected. Leukocytosis with eosinopenia can be a predictor of bacterial infection. It can be induced by stress reactions, Cushing’s syndrome, or the use of steroids. Pathological causes include burns and acute infections.

Does vasculitis cause shortness of breath?

You may develop shortness of breath or even cough up blood if vasculitis affects your lungs. Skin. Bleeding under the skin can show up as red spots. Vasculitis can also cause lumps or open sores on your skin.