What is a connective tissue nevus?
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What is a connective tissue nevus?
Connective tissue nevi (CTN) are hamartomas of the dermis, with the 3 main components being collagen, elastin, and proteoglycans. Each subtype can present as a solitary lesion or multiple lesions. They could present as part of systemic diseases or inherited disorders.
What is a Collagenoma?
Collagenoma is a type of connective tissue nevi, a rare hamartomatous malformation characterized by the predominant proliferation of normal collagen fibers and normal, decreased, or increased elastic fibers.
What causes connective tissue nevus?
A connective tissue naevus (American spelling nevus) is an uncommon skin lesion that occurs when the deeper layers of the skin do not develop correctly or the components of these layers occur in the wrong proportion. There may be too much collagen; this is called a collagenoma.
What causes Collagenoma?
Repetitive friction or rubbing of the skin can result in local irritation that leads to a connective-tissue reaction. This can cause an increased number of collagen fibers and a thickening of the dermis, known as collagenomas, or athlete’s nodules.
Is a nevus a hamartoma?
Nevus is defined as a type of hamartoma representing a circumscribed stable malformation of the skin that is not due to external causes and is presumed to be of hereditary origin.
What is Cowden syndrome?
Listen to pronunciation. (KOW-den SIN-drome) A rare inherited disorder marked by the presence of many benign (not cancer) growths called hamartomas and an increased risk of cancer. Hamartomas form in different parts of the body, especially the skin, mouth, and gastrointestinal tract.
Is hamartoma benign or malignant?
A benign (not cancer) growth made up of an abnormal mixture of cells and tissues normally found in the area of the body where the growth occurs.
What is Gardner syndrome?
Gardner syndrome is a rare condition that’s characterized by multiple colorectal polyps. People with Gardner syndrome have a high risk of developing colorectal cancer early in life. Though there is currently no known cure, there are ways to manage the condition and reduce the risk of cancer.
