What is equivalent to Lipitor?
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What is equivalent to Lipitor?
NAPLEX Question of the Week: Statin Equivalencies
Drug | Equivalent Dose (mg) by Intensity LDL reduction |
---|---|
Atorvastatin (Lipitor) | 10-20 |
Simvastatin (Zocor) | 20-40 |
Lovastatin (Mevacor) | 40-80 |
Pravastatin (Pravachol) | 40-80 |
Is rosuvastatin 10 mg the same as atorvastatin 20 mg?
Conclusion: In high-risk patients with hypercholesterolemia, rosuvastatin 10 mg was more efficacious than atorvastatin 20 mg at reducing LDL-C, enabling LDL-C goal achievement and improving other lipid parameters. Both treatments were well tolerated.
Is atorvastatin 10 mg the same as rosuvastatin 5 mg?
Conclusion Rosuvastatin 5 mg has a greater effect on serum LDL-C reduction as compared to atorvastatin 10 mg. However, its effect on reduction of serum total cholesterol, TG, and HDL-C is the same as atorvastatin.
Can I substitute rosuvastatin for atorvastatin?
Trials in patients with hypercholesterolaemia have shown that rosuvastatin is more effective than atorvastatin at reducing LDL-C and achieving US and/or European LDL-C goals over treatment periods ranging from 6 to 52 weeks [25-30].
What is the difference between Lipitor and atorvastatin?
Simply put, brand-name Lipitor and generic atorvastatin are the same medication, and, because of that, each is just as safe and effective as the other. Lipitor is made by Pfizer and generic Lipitor, which was first available in November 2011, is made by many different companies.
Is atorvastatin stronger than rosuvastatin?
Rosuvastatin was more efficacious than the same dose of atorvastatin (1:1 dose ratio) or a 2 times higher dose (1:2 dose ratio) of atorvastatin. There was no significant difference between rosuvastatin and a 4 times higher dose of atorvastatin (1:4 dose ratio).
What is the difference between Lipitor and rosuvastatin?
Crestor (rosuvastatin) is more potent and causes a more significant lowering of total cholesterol, but Crestor and Lipitor (atorvastatin) similarly decrease the buildup of plaques in the blood vessels.
Which is more safer atorvastatin or rosuvastatin?
In relation to renal function, atorvastatin was the safest statin as it resulted in the least number of patients at the end of 2 years of treatment with the new onset of microalbuminuria (10.9%) followed by rosuvastatin (14.3%) and then pravastatin (26.6%). Conclusion.
Are rosuvastatin and Lipitor the same?
How much does 10 mg Lipitor lower cholesterol?
These drugs decrease cholesterol synthesis by competitively inhibiting HMG-CoA reductase, the enzyme that catalyzes the rate-limiting step in the cholesterol biosynthetic pathway. Doses of 20 mg/d lovastatin or pravastatin or 10 mg/d simvastatin generally reduce plasma LDL cholesterol levels by about 20% to 30%.
Is Lipitor the best statin?
Lipitor is the most popular and most potent member of the statin family of drugs, which is the most widely prescribed class of medications in the United States.
Is 10 mg atorvastatin enough?
Adults—At first, 10 or 20 milligrams (mg) once a day. Some patients may need to start at 40 mg per day. Your doctor may increase your dose as needed. However, the dose is usually not more than 80 mg per day.
Is Lipitor the same as rosuvastatin?
Is rosuvastatin better than Lipitor?
Is 10mg atorvastatin enough?
Is 10 mg of Lipitor enough?
The typical dosage range of Lipitor is 10 mg to 80 mg taken once per day. The normal starting dosage is 10 mg to 20 mg taken once per day. But if you have very high cholesterol, your doctor may have you start with a dosage of 40 mg taken once per day.