What is the treatment regimen for TB?
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What is the treatment regimen for TB?
The preferred regimen for treating adults with TB remains a regimen consisting of an intensive phase of 2 months of isoniazid (INH), rifampin (RIF), pyrazinamide (PZA), and ethambutol (EMB) followed by a continuation phase of 4 months of INH and RIF.
What are the correct list of the four first line TB drugs for the treatment of Multi Drug Resistant TB?
Of the approved drugs, isoniazid (INH), rifampin (RIF), ethambutol (EMB), and pyrazinamide (PZA) are considered first-line anti-TB drugs and form the core of standard treatment regimens (Figure 6.4) (Table 6.2).
What is Rntcp treatment?
The Revised National TB Control Programme (RNTCP), based on the internationally recommended Directly Observed Treatment Short-course (DOTS) strategy, was launched in 1997 expanded across the country in a phased manner with support from World Bank and other development partners.
What regimen is given for new smear positive TB?
2. New cases. For treatment of new cases of pulmonary or extrapulmonary TB, WHO recommends a standardized regimen consisting of two phases. The initial (intensive) phase uses four drugs (rifampicin, isoniazid, pyrazinamide and ethambutol) administered for two months.
What is DMC in RNTCP?
Designated Microscopy Centre (DMC): The most peripheral laboratory under the RNTCP network is the designated microscopy centre (DMC) which serves a population of around 100,000 (50,000 in tribal and hilly areas).
What is the first-line drug of tuberculosis?
First-line agents for treatment of active TB consist of isoniazid, a rifamycin (rifampin or [less frequently] either rifapentine or rifabutin), pyrazinamide, and ethambutol; in addition, moxifloxacin is a first-line agent when administered in combination with isoniazid, rifapentine, and pyrazinamide [6].
WHO TB drugs classification?
2. Classifications
| (1) WHO 2011 TB drugs classification | |
|---|---|
| Group 1 First-line oral anti-TB drugs | • Isoniazid • Rifampicin • Ethambutol • Pyrazinamide |
| Group 2 Injectable anti-TB drugs (injectable or parenteral agents) | • Streptomycin • Kanamycin • Amikacin • Capreomycin |
What are the 2 formulations of anti TB drugs?
Currently, the WHO Model List of Essential Drugs includes two-drug formulations (INH + RIF and INH + ethambutol), three-drug formulations (INH + RIF + ethambutol and INH + RIF + pyrazinamide) and a four-drug formulation (INH + RIF + ethambutol + pyrazinamide) [13].
What is the difference between rifampin and Rifampicin?
Rifampicin, also known as rifampin, is an ansamycin antibiotic used to treat several types of bacterial infections, including tuberculosis (TB), Mycobacterium avium complex, leprosy, and Legionnaires’ disease.
What is DST in TB?
Drug susceptibility testing (DST) of Mycobacterium tuberculosis is generally carried out after a culture is isolated from a clinical specimen. This takes a long time, first to isolate a culture and then to perform drug susceptibility testing (indirect DST).
