What are the serious side effects of indomethacin?

What are the serious side effects of indomethacin?

Serious side effects of Indocin may include heart attack, stroke, skin changes (paleness, blisters, rash, and hives), weight gain, swelling, shortness of breath, tachycardia, unusual bleeding (including GI bleeding), jaundice, stomach pain, and pain with urination, bloody urine, blurry vision, and back pain.

What does indomethacin do to your body?

This medication is known as a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body’s production of certain natural substances that cause inflammation. This effect helps to decrease swelling and pain.

Is indomethacin high risk?

People who take nonsteroidal anti-inflammatory drugs (NSAIDs) (other than aspirin) such as indomethacin may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death.

What is long term use of indomethacin?

Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID). NSAIDs may increase your risk of heart attack, heart failure, or stroke. This risk may be higher if you’re taking it long term, at high doses, or if you already have heart problems or risk factors for heart disease, such as high blood pressure.

How long can you safely take indomethacin?

Adults—75 to 150 milligrams (mg) per day, divided into three or four equal doses, and taken for 1 to 2 weeks as determined by your doctor.

What drugs should not be taken with indomethacin?

Don’t take indomethacin with the following NSAIDs unless expressly directed to by your healthcare provider:

  • Advil, Motrin (ibuprofen)
  • Aleve (naproxen)
  • Aspirin.
  • Celebrex (celecoxib)
  • Mobic (meloxicam)
  • Voltaren, Zorvolex, Zipsor (diclofenac)
  • Ketorolac2.

How long is it safe to take indomethacin?

How many days can you take indomethacin?

Typical dosing for indomethacin (Indocin) Shoulder pain: Take 75 mg to 150 mg by mouth or rectally per day. This total dose should be split into 3 or 4 smaller doses and taken throughout the day every 6 to 8 hours. This should be continued until your symptoms have gotten better but no more than 7 to 14 days.

Is indomethacin hard on the kidneys?

Any medication may have some drug interaction that affect the kidneys. Of the medication that you take, Indomethacin can cause kidney function to decline.

Is it okay to take an indomethacin everyday?

Adults—25 milligrams (mg) two or three times a day. Your doctor may increase your dose by 25 or 50 mg per day, as needed. However, the total dose is usually not more than 200 mg per day.

Can you drink coffee with indomethacin?

“The results show that the combination of caffeine with indomethacin , an inhibitor of prostaglandin synthesis, mediated caffeine’s effect by increasing cellular viability and lowering superoxide anion production and DNA fragmentation.”

What can I take instead of indomethacin?

Naproxen.

  • Indocin.
  • Ibuprofen.
  • Methylprednisolone.
  • Advil.
  • MethylPREDNISolone Dose Pack.
  • How long should I take indomethacin for gout?

    This total dose should be split into 3 or 4 smaller doses and taken throughout the day every 6 to 8 hours. This should be continued until your symptoms have gotten better but no more than 7 to 14 days.

    How long can you stay on indomethacin?

    How long should you take indomethacin for gout?

    Is indomethacin safe to take daily?

    For safe and effective use of this medicine, do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Taking too much of this medicine may increase the chance of unwanted effects.

    • September 6, 2022