What does the AhR gene do?
Table of Contents
What does the AhR gene do?
UniProtKB/Swiss-Prot Summary for AHR Gene Regulates a variety of biological processes, including angiogenesis, hematopoiesis, drug and lipid metabolism, cell motility and immune modulation (PubMed:12213388).
What is AhR in immunology?
AhR is a ligand-activated transcription factor that promotes Treg cell development and suppression of pro-inflammatory cytokine production in dendritic cells, altering the course of adaptive immune response and the development of immunopathology.
What is an AhR agonist?
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor with important functions in the immune response and cancer. AHR agonists are provided by the environment, the commensal flora and the metabolism.
What does the Ah receptor do?
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that integrates environmental, dietary, microbial and metabolic cues to control complex transcriptional programmes in a ligand-specific, cell-type-specific and context-specific manner.
Which one is activator of the AhR pathway?
One of the key target genes activated in the AhR genomic pathway is the AhR repressor, AhRR [16], [17], [18] (Fig.
Where is the AHR receptor found?
The AhR protein contains several domains critical for function and is classified as a member of the basic helix-loop-helix/Per-Arnt-Sim (bHLH/PAS) family of transcription factors. The bHLH motif is located in the N-terminal of the protein and is a common entity in a variety of transcription factors.
Where is the aryl hydrocarbon receptor?
Protein domains found in the aryl hydrocarbon receptor (AHR) and aryl hydrocarbon receptor nuclear translocator (ARNT). The nuclear localization sequence (NLS) and nuclear export sequence (NES) are found within the basic helix loop helix (bHLH) region. The bHLH also plays a critical role in DNA binding.
Where are AhR receptors located?
Aryl hydrocarbon receptor
AHR | |
---|---|
External IDs | OMIM: 600253 MGI: 105043 HomoloGene: 1224 GeneCards: AHR |
Gene location (Human) Chr. Chromosome 7 (human) Band 7p21.1 Start 16,916,359 bp End 17,346,152 bp | |
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12 A3|12 15.78 cM Start 35,547,973 bp End 35,585,037 bp |
Is AhR legitimate?
It is 100 % a scam.
Where is the AhR receptor?
Is AHR a government agency?
No. AHR is a Nashville-based 501(c) 3 nonprofit organization. We are a chartered member of NeighborWorks® and we are dedicated to building partnerships with individual families, neighborhood leaders and others who care about and invest in Middle Tennessee.
Is American Hope resources com legit?
The Better Business Bureau has issued an alert and an F rating on a company called American Hope Resources, which has nearly 90 complaints. Consumers say they were contacted on Facebook by someone posing as someone they know, telling them they can get federal government grant support.
Is Ahr American Hope resources legit?
THIS IS A SCAM My friend’s identity was stolen from Facebook and used to contact me and tried to recruit me to apply for a grant,since she had received over $100,000 and didn’t have to pay it back,I was then linked to an agent who asked for lots of personal information.