What is Nitrostyrene used for?
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What is Nitrostyrene used for?
β-Nitrostyrene is an aromatic compound and a nitroalkene used in the synthesis of indigo dye and the slimicide bromo-nitrostyrene.
How to make Nitrostyrene?
Nitrostyrene can be prepared by the condensation of benzaldehyde and nitromethane. This may be accomplished by the use of small amounts of a primary aliphatic amine,1 a method which requires a number of days for the reaction to go to completion, or preferably by the use of alkali as first discovered by Thiele.
Are styrene fumes toxic?
Summary of Health Effects Styrene is readily absorbed and can result in toxicity following inhalation and dermal exposure [1-3]. Although no cases of styrene ingestion have been reported in humans, it is expected to give rise to systemic toxicity, similar to that seen following inhalation [1, 2].
Is styrene a hazardous substance?
Acute Health Effects The following acute (short-term) health effects may occur immediately or shortly after exposure to Styrene Monomer: ► Styrene Monomer can irritate the skin, causing a rash, dryness, redness and burning feeling on contact. ► Exposure can irritate the eyes, nose and throat.
How do you get styrene poisoning?
The major routes of occupational exposure to styrene are by inhalation of vapours or by dermal absorption [1-3]. Styrene can also result in toxicity by ingestion. However, ingestion of styrene is not a significant occupational hazard [1].
Can your body get rid of styrene?
Styrene is extensively metabolized by the body enzymes into other chemicals that are excreted through urine.
Is styrene poisonous?
Acute exposure to styrene by inhalation can give rise to irritation of the mucous membranes of the nose and throat, increased nasal secretion, wheezing and coughing. A more severe exposure to styrene can lead to the onset of CNS depression, the effects of which are commonly termed “styrene sickness”.
How long does styrene stay in your body?
After an 8-hour exposure of workers to styrene at concentrations of 26–130 mg/m3 (6.1–30.5 ppm), both metabolites have a half-life of about 2.5 hour for the first phase and 30 hours for the second (35). These compounds are used in assessing occupational exposure to styrene.
Does styrene leave your body?
Leave your body: Once in your body, styrene is broken down into other chemicals. Most of these other chemicals leave your body in the urine within few days.
