What is postsplenectomy sepsis?
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What is postsplenectomy sepsis?
The major long-term complication of splenectomy is OPSI, also known as post-splenectomy sepsis syndrome, which is defined as a generalized non-specific flu-like prodrome followed by rapid deterioration to full-blown fulminant septic shock within 24-48 hours of the onset [9].
Which client has a need for prophylactic antibiotic therapy prior to dental manipulations?
Antibiotic prophylaxis is warranted for some patients with cardiac conditions and compromised immunity when undergoing dental procedures that involve the manipulation of gingival tissue or the periapical region of teeth or perforation of oral mucosa.
How can OPSI be prevented?
Strategies to prevent OPSI include education; vaccination against S. pneumoniae, Haemophilus influenzae type b, Neisseria meningitidis and influenza (annually); and daily antibiotics for at least 2 years postsplenectomy and emergency antibiotics in case of infection.
Is clindamycin a prophylactic antibiotic?
Clindamycin is a broad-spectrum antibiotic with activity against aerobic, anaerobic, and beta-lactamase-producing pathogens. This antibiotic has been used for many years as prophylactic treatment during dental procedures to prevent endocarditis.
What does OPSI mean?
OPSI
| Acronym | Definition |
|---|---|
| OPSI | Overwhelming Post-Splenectomy Infection |
| OPSI | Ohio Patient Safety Institute (Ohio Health Council) |
| OPSI | Open PC Server Integration |
| OPSI | Occidental Power Services Inc. (Houston, TX) |
What is overwhelming Postsplenectomy infection?
Overwhelming post-splenectomy infection (OPSI) is a serious disease that can progress from a mild flu-like illness to fulminant sepsis in a short time period. However, recognition and clinical management of OPSI is not well established.
What are prophylactic antibiotics used in dentistry?
Antibiotic prophylaxis has been used in dentistry for patients at risk of infective endocarditis or prosthetic joint infection. The scientific rationale for prophylaxis was to eliminate or reduce transient bacteraemia caused by invasive dental procedures.
What is post-splenectomy?
Post-splenectomy complications can occur after surgery to remove the spleen. Complications may include: Blood clots. Destruction of red blood cells. Increased risk for severe infections from bacteria such as Streptococcus pneumoniae and Neisseria meningitidis.
What is OPSI in surgery?
An overwhelming post-splenectomy infection (OPSI) is a rare but rapidly fatal infection occurring in individuals following removal (or permanent dysfunction) of the spleen.
What is Splenorrhaphy?
[ splĭ-nôr′ə-fē ] n. Suture of a ruptured spleen.
How common are Splenectomies?
Although preservation of the spleen following abdominal trauma and spleen-preserving surgical procedures have become gold standards, about 22,000 splenectomies are still conducted annually in the USA. Infections, mostly by encapsulated organisms, are the most well-known complications following splenectomy.
What is endocarditis prophylaxis?
Endocarditis prophylaxis seeks to prevent IE by administering antibiotics to high-risk patients when they undergo procedures that can induce bacteremia.
What is meant by prophylactic antibiotics?
Prophylactic antibiotics are antibiotics that you take to prevent infection. Normally, you take antibiotics when you have an infection. Your doctor may give you antibiotics ahead of time to prevent infection in some situations where your risk of infection is high.
What is antibiotic prophylaxis for dental procedures?
What Is Antibiotic Prophylaxis? Antibiotic prophylaxis (or premedication) is simply the taking of antibiotics before some dental procedures such as teeth cleaning, tooth extractions, root canals, and deep cleaning between the tooth root and gums to prevent infection.
What vaccine is given after splenectomy?
Pneumococcal, meningococcal, and Haemophilus influenzae (Hib) vaccinations are indicated for patients after splenectomy.
What vaccines should be given before splenectomy?
Ideally, vaccination with both types of pneumococcal (conjugate [PCV] and polysaccharide [PPSV]), both types of meningococcal (MenACWY and MenB), and Hib vaccine should all be completed at least 2 weeks before a scheduled splenectomy, if time permits.
What is prophylaxis dental treatment?
A dental prophylaxis is a cleaning procedure performed to thoroughly clean the teeth. Prophylaxis is an important dental treatment for halting the progression of periodontal disease and gingivitis.
