What is procainamide used for in ACLS?

What is procainamide used for in ACLS?

Procainamide is a medication used to manage and treat ventricular arrhythmias, supraventricular arrhythmias, atrial flutter, atrial fibrillation, AV nodal re-entrant tachycardia, and Wolf-Parkinson-White syndrome. It is a Class 1A antiarrhythmic agent.

When do you give procainamide?

Procainamide should be used only to treat life-threatening arrhythmias (irregular heartbeats). Procainamide may cause a decrease in the number of cells in your bone marrow. Procainamide may also cause symptoms of lupus. Keep all appointments with your doctor and the laboratory.

How do you administer procainamide?

Intravenous injection or infusion is preferred over intramuscular injection. Intravenous injection: Each 100 mg of procainamide must be diluted in 10 ml of sterile water for injection or D5W injection. Inject by slow IV push at a rate not to exceed 50 mg/minute.

What is a contraindication to the use of procainamide in the management of stable wide complex tachycardia?

Procainamide is contraindicated in patients with torsades de pointes, second- or third-degree AV block without a functioning pacemaker, or systemic lupus erythematosus and in patients hypersensitive to the anesthetic procaine.

When do you use amiodarone vs procainamide?

Interpretation: The results of this trial indicate that procainamide is better tolerated and more efficacious acutely than amiodarone in the treatment of hemodynamically stable wide complex tachycardia (presumably VT), including in patients with structural heart disease.

What is procainamide given for?

Procainamide injection is used to treat irregular heartbeats and to slow an overactive heart. When the heart has a normal heartbeat (rhythm), it will work more efficiently. Procainamide works by slowing the nerve impulses in the heart and reducing the sensitivity of heart tissues.

Does procainamide lower blood pressure?

As outlined above, procainamide loading decreased arterial and central venous pressures and increased heart rate. Both the frequency and amplitude of sympathetic burst dis- charges in the neurogram decreased, and in this subject, SNA decreased from 155 units/min to 63 units/min after procainamide infusion.

Does procainamide cause hypotension?

Side effects These adverse effects are ventricular dysrhythmia, bradycardia, hypotension and shock. The adverse effects occur even more often if the daily doses are increased. Procainamide may also lead to drug fever and other allergic responses.

What is the most common adverse effect of procainamide?

Common side effects of Pronestyl (procainamide hydrochloride) include nausea, vomiting, loss of appetite, diarrhea, bitter taste in the mouth, dizziness, tired feeling, flushing (warmth, redness, or tingly feeling), and itching or rash.

Do you use amiodarone for SVT?

Background— Intravenous amiodarone and procainamide are both used as therapies for refractory supraventricular tachycardia (SVT).

Does procainamide increase heart rate?

As outlined above, procainamide loading decreased arterial and central venous pressures and increased heart rate.

Does procainamide decrease heart rate?

PROCAINAMIDE (proe kane A mide) is an antiarrhythmic drug. It helps make your heart beat regularly. This medicine also helps to slow rapid heartbeats.

Can procainamide cause v tach?

This case: Demonstrates that procainamide may cause the first emergence of sustained monomorphic VT in a patient with no previous history of VT; and Emphasizes the utility of programmed ventricular stimulation in providing direct evidence for drug mediated exacerbation of the ventricular arrhythmia.

Does procainamide cause bradycardia?

The adverse effects of procainamide include cardiac toxicity, bradycardia, hypotension, drug-induced lupus erythematosus-like syndrome, and blood dyscrasias. QRS, QTc, and PR prolongation are the most potentially harmful cardiac side effects of procainamide and may become worse when levels of procainamide rise.