What is sevelamer used for?

What is sevelamer used for?

Sevelamer is used to treat hyperphosphatemia (too much phosphate in the blood) in patients with chronic kidney disease who are on dialysis. This medicine is available only with your doctor’s prescription. This product is available in the following dosage forms: Powder for Suspension.

What is the action of sevelamer?

MECHANISM OF ACTION Sevelamer binds dietary phosphate within the gastrointestinal tract. It contains multiple amines separated by one carbon from the polymer backbone. These amines exist in a protonated form in the intestine and interact with phosphate molecules through ionic and hydrogen bonding.

What happens if you take too much sevelamer?

Gastrointestinal effects: Sevelamer can cause severe problems in the digestive tract, such as blockages and holes. Tell your doctor if you have a history of swallowing disorders, digestive tract surgery, or severe constipation.

How does sevelamer carbonate work?

Sevelamer carbonate (Renvela) is a phosphate binder. It binds to the phosphates in your food before they can be absorbed. This lowers your blood phosphorus levels to help protect your kidneys and bones.

When do you give sevelamer?

Sevelamer comes as a tablet and as a powder for suspension to take by mouth. It is usually taken three times a day with meals. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take sevelamer exactly as directed.

When is sevelamer indicated?

Renvela® (sevelamer carbonate) is indicated for the control of serum phosphorus in adults and children 6 years of age and older with chronic kidney disease (CKD) on dialysis. Starting Dose for Adult Patients Not Taking a Phosphate Binder.

What is a normal phosphorus level?

Normal values range from: Adults: 2.8 to 4.5 mg/dL. Children: 4.0 to 7.0 mg/dL.

When is the best time to take sevelamer?

Sevelamer comes as a tablet and as a powder for suspension to take by mouth. It is usually taken three times a day with meals.

Does sevelamer increase calcium?

Sevelamer reduces calcium load and maintains a low calcium-phosphorus ion product in dialysis patients.

How do you take sevelamer tablets?

It is recommended to take 1-2 tablets (based on individual needs) thrice daily. It is important to take it with meals because Sevelamer 800 Tablet works by binding to phosphate from food. Take it exactly as advised by your doctor.

Why is albumin given during dialysis?

It provides the body with the protein needed to both maintain growth and repair tissues. During a dialysis treatment, the albumin in your blood also helps with fluid removal. It helps “pull” extra fluid from swollen tissues back into the blood, where it can then be removed by the dialyzer.

Which phosphate binder is the best?

Calcium carbonate is the most commonly used phosphate binder, but clinicians are increasingly prescribing the more expensive, non-calcium-based phosphate binders, particularly sevelamer.

What are symptoms of high phosphorus?

Most people with high phosphate levels don’t have symptoms. In some people with chronic kidney disease, high phosphate levels cause calcium levels in the blood to drop….What are the symptoms?

• muscle cramps or spasms.
• numbness and tingling around the mouth.
• bone and joint pain.
• weak bones.
• rash.
• itchy skin.

Is urine high in phosphorus?

Fifty to 60 percent of the phosphorus in human waste is in urine, which is typically very low in pathogens. A year’s worth of urine from just one person contains enough phosphorus to produce at least half of their annual food requirement.

How is sevelamer administered?

Can sevelamer be taken on an empty stomach?

Renvela should be taken with food and not on an empty stomach. Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Bowel obstruction.

What is a normal albumin level?

The normal range is 3.4 to 5.4 g/dL (34 to 54 g/L). Normal value ranges may vary slightly among different laboratories. Some labs use different measurements or test different samples. Talk to your provider about the meaning of your specific test results.

Is albumin high or low in kidney failure?

Why does a low serum albumin increase the risk for reaching kidney failure? Many studies have shown that chronic kidney disease (CKD) patients with a low serum albumin have an increased risk for reaching kidney failure as compared to patients with a normal serum albumin.

Does dialysis remove phosphorus?

Yes. Dialysis can remove some phosphorus from your blood. It is important for you to understand how to limit build-up of phosphorus between your dialysis treatments.