What is the pathology of hepatitis B?

What is the pathology of hepatitis B?

The pathogenesis and clinical manifestations of hepatitis B are due to the interaction of the virus and the host immune system, which leads to liver injury and, potentially, cirrhosis and hepatocellular carcinoma. Patients can have either an acute symptomatic disease or an asymptomatic disease.

What is the pathology of hepatitis?

Hepatitis is defined as inflammation of the liver that can result from a variety of causes such as heavy alcohol use, autoimmune, drugs, or toxins. However, the most frequent cause of hepatitis is due to a viral infection and is referred to as viral hepatitis.

What causes hepatitis B in the liver?

Hepatitis B is a vaccine-preventable liver infection caused by the hepatitis B virus (HBV). Hepatitis B is spread when blood, semen, or other body fluids from a person infected with the virus enters the body of someone who is not infected.

What is differential diagnosis of hepatitis B?

Hepatitis B must be differentiated from other diseases that cause fever, nausea, vomiting, jaundice, hepatomegaly, icteric sclera, elevated ALT, and elevated AST, such as other types of viral hepatitis, alcoholic hepatitis, and autoimmune hepatitis.

What is the test for hepatitis B?

The “Hepatitis B Panel” of Blood Tests HBsAg (Hepatitis B surface antigen) – A “positive” or “reactive” HBsAg test result means that the person is infected with hepatitis B. This test can detect the actual presence of the hepatitis B virus (called the “surface antigen”) in your blood.

How does hepatitis affect the liver?

Viral hepatitis is an infection that causes liver inflammation and damage. Inflammation is swelling that occurs when tissues of the body become injured or infected. Inflammation can damage organs. Researchers have discovered several different viruses link that cause hepatitis, including hepatitis A, B, C, D, and E.

How does hepatitis B affect the liver?

Hepatitis B is a serious liver infection that causes inflammation (swelling and reddening) that can lead to liver damage. Hepatitis B, also called HBV and Hep B, can cause cirrhosis (hardening or scarring), liver cancer and even death.

What are the complications of hepatitis B?

Having a chronic HBV infection can lead to serious complications, such as: Scarring of the liver (cirrhosis). The inflammation associated with a hepatitis B infection can lead to extensive liver scarring (cirrhosis), which may impair the liver’s ability to function. Liver cancer.

Can hepatitis B test false positive?

There are reports of false positivity of HBsAg among healthy blood donors, however, scanty data could be found for adults undergoing health screening programs. This article aims to report the false positive results of HBsAg due to the recent Hepatitis B vaccine among healthy male adults.

How is hepatitis B diagnosed?

Blood tests can detect signs of the hepatitis B virus in your body and tell your doctor whether it’s acute or chronic. A simple blood test can also determine if you’re immune to the condition. Liver ultrasound.

Is hepatitis B DNA or RNA?

The hepatitis B virus (HBV) is a small DNA virus with unusual features similar to retroviruses. It is a prototype virus of the Hepadnaviridae family.

What is the size of hepatitis B?

The infectious component of hepatitis B (HB) virus (HBV), the Dane particle, has a diameter of ≈44 nm and consists of a double-layered capsid particle enclosing a circular, incomplete double-stranded DNA genome.

How does hepatitis B damage liver?

Cirrhosis: With a chronic HBV infection, large areas of the liver can become permanently scarred and nodules may form. Blood cannot flow freely through scarred liver tissue. This causes the liver to begin to shrink and become hard. Liver Failure: If cirrhosis becomes very severe, liver failure can occur.

How does hepatitis B infect the liver cells?

When the virus enters the body of a new host it’s initial response, if it’s gets past the immune system, is to infect a liver cell. To do this the virus attaches to a liver cells membrane and the core particle enters the liver cell.